Evidence map›Paper›PMID 40138153›Full record

ReviewCurrent oncology reports2025

Advancing Glioma Management: The Pivotal Role of Surgical Neuro-Oncology in Driving Innovation and Translational Research.

Jack M Shireman, Simon G Ammanuel, Mahua Dey

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jack M ShiremanDepartment of Neurosurgery, University of Wisconsin School of Medicine & Public Health, UW Carbone Cancer Center, Madison, WI, USA.
Simon G AmmanuelDepartment of Neurosurgery, University of Wisconsin School of Medicine & Public Health, UW Carbone Cancer Center, Madison, WI, USA.
Mahua DeyDepartment of Neurosurgery, University of Wisconsin School of Medicine & Public Health, UW Carbone Cancer Center, Madison, WI, USA. dey@neurosurgery.wisc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of the reviewThis study aims to assess the evolution of the role of surgery in advancing the treatment paradigm of primary central nervous system malignancies, gliomas. RECENT

findingsDiagnostic and therapeutic surgical intervention is the cornerstone for management of all gliomas. Current treatment guidelines for all gliomas include maximal safe resection, with concurrent and adjuvant chemo/radiotherapy, or other targeted molecular therapies, for high-grade gliomas and subsets of low-grade gliomas dependent on mutation profiling and IDH status. The extent of surgical resection affects overall survival across all grades of gliomas. Recently, several technological advances have augmented a surgeon's ability to push the boundaries of extent of resection, while also opening the door for novel intraoperative diagnostic and therapeutic interventions. Increasingly surgery is playing a pivotal role in the management of gliomas from diagnosis to therapeutic intervention, to drug delivery and progression monitoring. Novel technological advances such as advanced image guidance, fluorescence markers, intraoperative functional mapping, histological identification, and intraoperative radiation and drug delivery, provide a fertile ground for combining innovative modalities together to drive better treatment strategies and outcomes for patients.

Indexed as

Brain NeoplasmsGliomaHumansNeurosurgical ProceduresSurgical OncologyTranslational Research, BiomedicalGlioma intraoperative therapySurgical clinical trialsSurgical neuro-oncologyTranslational research

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.