Evidence map›Paper›PMID 40138100›Full record

ArticleRheumatology and therapy2025

The Relationship Between Metabolic Syndrome and Pain Catastrophizing in Psoriatic Arthritis.

Damiano Currado, Onorina Berardicurti, Francesca Saracino, Francesca Trunfio, Lyubomyra Kun, Annalisa Marino, Erika Corberi, Ludovica Lamberti, Piero Ruscitti, Vasiliki Liakouli and 9 more

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Article in Rheumatology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  3. Review
  4. Article
  5. Review
  6. Article
  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Damiano Currado *Unit of Allergology, Clinical Immunology and Rheumatology, Department of Medicine, University Campus Bio-Medico di Roma, via Alvaro del Portillo 21, 00128, Rome, Italy.
Onorina Berardicurti *Unit of Allergology, Clinical Immunology and Rheumatology, Department of Medicine, University Campus Bio-Medico di Roma, via Alvaro del Portillo 21, 00128, Rome, Italy.
Francesca SaracinoUnit of Allergology, Clinical Immunology and Rheumatology, Department of Medicine, University Campus Bio-Medico di Roma, via Alvaro del Portillo 21, 00128, Rome, Italy.
Francesca TrunfioUnit of Allergology, Clinical Immunology and Rheumatology, Department of Medicine, University Campus Bio-Medico di Roma, via Alvaro del Portillo 21, 00128, Rome, Italy.
Lyubomyra KunUnit of Allergology, Clinical Immunology and Rheumatology, Department of Medicine, University Campus Bio-Medico di Roma, via Alvaro del Portillo 21, 00128, Rome, Italy.
Annalisa MarinoUnit of Allergology, Clinical Immunology and Rheumatology, Department of Medicine, University Campus Bio-Medico di Roma, via Alvaro del Portillo 21, 00128, Rome, Italy. a.marino@policlinicocampus.it.ORCID http://orcid.org/0000-0002-2511-7374
Erika CorberiUnit of Allergology, Clinical Immunology and Rheumatology, Department of Medicine, University Campus Bio-Medico di Roma, via Alvaro del Portillo 21, 00128, Rome, Italy.
Ludovica LambertiUnit of Allergology, Clinical Immunology and Rheumatology, Department of Medicine, University Campus Bio-Medico di Roma, via Alvaro del Portillo 21, 00128, Rome, Italy.
Piero RuscittiDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Vasiliki LiakouliRheumatology Unit, Department of Precision Medicine, University of Campania L. Vanvitelli, Caserta, Italy.
Marta VadaccaClinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Biomedico, Rome, Italy.
Amelia RigonClinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Biomedico, Rome, Italy.
Luisa ArcareseClinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Biomedico, Rome, Italy.
Manuela PietramaleUnit of Allergology, Clinical Immunology and Rheumatology, Department of Medicine, University Campus Bio-Medico di Roma, via Alvaro del Portillo 21, 00128, Rome, Italy.
Francesco De VincenzoDepartment of Human Sciences, European University of Rome, Rome, Italy.
Marta VomeroUnit of Allergology, Clinical Immunology and Rheumatology, Department of Medicine, University Campus Bio-Medico di Roma, via Alvaro del Portillo 21, 00128, Rome, Italy.
Francesco CicciaRheumatology Unit, Department of Precision Medicine, University of Campania L. Vanvitelli, Caserta, Italy.
Roberto GiacomelliUnit of Allergology, Clinical Immunology and Rheumatology, Department of Medicine, University Campus Bio-Medico di Roma, via Alvaro del Portillo 21, 00128, Rome, Italy.
Luca NavariniUnit of Allergology, Clinical Immunology and Rheumatology, Department of Medicine, University Campus Bio-Medico di Roma, via Alvaro del Portillo 21, 00128, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPsoriatic arthritis (PsA) is a complex inflammatory disease often associated with metabolic syndrome (MetS). It has been demonstrated that pain catastrophizing (PC), characterized by an exaggerated negative cognitive and emotional response to actual or anticipated pain, impacts the achievement of remission and therapy discontinuation in patients with PsA. In this study, we evaluate the potential role of MetS, the most prevalent comorbidity in PsA, in influencing PC in patients with PsA.

methodsWe conducted a cross-sectional, observational study on 170 patients with PsA who met the Classification Criteria for PsA and MetS criteria. Data on disease activity, PC, and comorbidities were collected and analyzed using univariable and multivariable regressions.

resultsOur results indicate a significant association between MetS and elevated PC levels in patients with PsA. Univariable analysis identified female gender, fibromyalgia, and higher Disease Activity for Psoriatic Arthritis (DAPSA) scores as factors associated with increased PC. Multivariable analysis, adjusted for age, sex, fibromyalgia, and DAPSA, confirmed that MetS independently correlates with higher PC levels (b = 8.84, 95% CI 4.66-13.02, p < 0.0001) and its domains (helplessness, rumination, magnification).

conclusionsThese findings suggest that MetS significantly impacts PC in PsA, underscoring the need for a multidisciplinary approach to patient management. This study highlights the importance of addressing MetS to reduce pain catastrophizing and enhance disease management in PsA.

Indexed as

Metabolic syndromePain catastrophizingPsoriatic arthritis

Identifiers

PMID40138100
PMCPMC12084470

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.