Evidence map›Paper›PMID 40138069›Full record

ArticleEating and weight disorders : EWD2025

Therapeutic immersion: a single-subject study on virtual reality multisensory experiences for mitigating body disturbance in anorexia nervosa.

Giulia Brizzi, Margherita Boltri, Rebecca Guglielmini, Gianluca Castelnuovo, Leonardo Mendolicchio, Giuseppe Riva

Abstract readCase Reports
In one paragraph

Article in Eating and weight disorders : EWD, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giulia BrizziApplied Technology for Neuro- Psychology Laboratory, IRCCS Istituto Auxologico Italiano, 20149, Milan, Italy. giuliabrizzi97@gmail.com.
Margherita BoltriU.O. dei Disturbi del Comportamento Alimentare, I.R.C.C.S. Istituto Auxologico Italiano, Ospedale San Giuseppe, 28824, Piancavallo, VCO, Italy.
Rebecca GuglielminiExperimental Laboratory for Metabolic Neurosciences Research, I.R.C.C.S. Istituto Auxologico Italiano, 28824, Piancavallo, VCO, Italy.
Gianluca CastelnuovoDepartment of Psychology, Università Cattolica del Sacro Cuore, Largo Gemelli, 20121, Milan, Italy.
Leonardo MendolicchioU.O. dei Disturbi del Comportamento Alimentare, I.R.C.C.S. Istituto Auxologico Italiano, Ospedale San Giuseppe, 28824, Piancavallo, VCO, Italy.
Giuseppe RivaApplied Technology for Neuro- Psychology Laboratory, IRCCS Istituto Auxologico Italiano, 20149, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anorexia Nervosa (AN) is a mental health condition marked by reduced food consumption, intense fear of weight gain, and distorted body experience. Virtual Reality (VR)-based techniques-i.e., Body-Swapping and Mirror Exposure techniques-offer promising avenues for addressing body disturbance in AN, allowing patients to embody virtual bodies varying in size and shape. We used a single-subject experimental design to explore the potential of virtual reality multisensory experiences for mitigating body disturbance in AN. We examine the case of a 24-year-old female hospitalized with restrictive Anorexia Nervosa who underwent a novel body-focused VR intervention alongside the hospital's standard care. The intervention included six bi-weekly sessions, wherein the patient was immersed in a VR environment that allowed her to embody a virtual body that matched a healthy weight range. Through interactions with a virtual mirror, the patient was encouraged to concentrate on the body's positive aspects and functional abilities, thinking about its significance in her past, current, and anticipated future activities (Functional Mirror Exposure). The patient reported reduced body dissatisfaction, negative beliefs, and body misperception. These changes endorse using immersive, multisensory, and embodied experiences to alter body consciousness and body-self relationship. Results preliminary support the transformative potential of VR in improving traditional approaches to assess and alter body disturbance.Level of evidence Level IV.

Indexed as

Anorexia NervosaBody ImageVirtual RealityVirtual Reality Exposure TherapyFemaleHumansSelf ConceptYoung AdultAllocentricAnorexia nervosaBodyBody illusionEgocentricMirror exposureMultisensory integrationVirtual reality

Identifiers

PMID40138069
PMCPMC11946939

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.