Evidence map›Paper›PMID 40138040›Full record

ArticleMarine biotechnology (New York, N.Y.)2025

Overexpression of Plastid Acetyl-CoA Carboxylase Confers Stress Tolerances with Increased Levels of Unsaturated Fatty Acids in the Marine Diatom Phaeodactylum tricornutum.

Masakazu Toyoshima, Hajime Okuda, Yuya Okada, Kohei Yoneda, Ginga Shimakawa, Yusuke Matsuda

Abstract read
PubMed Publisher
In one paragraph

Article in Marine biotechnology (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masakazu Toyoshima *Department of Bioscience, School of Biological and Environmental Sciences, Kwansei Gakuin University, 1 Gakuen Uegahara, Sanda, Hyogo, 669-1330, Japan.ORCID http://orcid.org/0000-0002-6322-7806
Hajime Okuda *Department of Bioscience, School of Biological and Environmental Sciences, Kwansei Gakuin University, 1 Gakuen Uegahara, Sanda, Hyogo, 669-1330, Japan.
Yuya OkadaDepartment of Bioscience, School of Biological and Environmental Sciences, Kwansei Gakuin University, 1 Gakuen Uegahara, Sanda, Hyogo, 669-1330, Japan.
Kohei YonedaInstitute of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8577, Japan.ORCID http://orcid.org/0000-0003-0734-0617
Ginga ShimakawaDepartment of Bioscience, School of Biological and Environmental Sciences, Kwansei Gakuin University, 1 Gakuen Uegahara, Sanda, Hyogo, 669-1330, Japan.ORCID http://orcid.org/0000-0002-8557-2096
Yusuke MatsudaDepartment of Bioscience, School of Biological and Environmental Sciences, Kwansei Gakuin University, 1 Gakuen Uegahara, Sanda, Hyogo, 669-1330, Japan. yusuke@kwansei.ac.jp.ORCID http://orcid.org/0000-0002-1892-4397

Funding

Japan Science and Technology Agency JPMJCR20E1Japan Society for the Promotion of Science 19H01153New Energy and Industrial Technology Development Organization JPNP17005
6 · The paper itself

Abstract

Acetyl-coenzyme A carboxylases (ACCs) catalyze the initial reaction of fatty acid (FA) biosynthesis. The marine diatom Phaeodactylum tricornutum has two nuclear-encoded ACCs (PtACC1 (Phatr3_EG01955) and PtACC2 (Phatr3_J55209)), both which are homomeric and predicted to be localized in the plastids and the cytosol, respectively. In this study, we focused on stromal ACC1 by constructing P. tricornutum strains expressing GFP-tagged PtACC1 (ACCG strains) and confirmed that PtACC1 was localized in or around the pyrenoid. Here, we showed that unsaturated FAs (UFAs) composing the thylakoid membrane lipids increased in PtACC1 strains grown under high light conditions (190 µmol photons m

Indexed as

Acetyl-CoA CarboxylaseDiatomsFatty Acids, UnsaturatedPlastidsLightOxidative StressPhotosystem II Protein ComplexStress, PhysiologicalThylakoidsTriglyceridesAcetyl-CoA CarboxylaseFatty Acids, UnsaturatedPhotosystem II Protein ComplexTriglyceridesAcetyl-CoA carboxylaseOxidative stressTAGUnsaturated fatty acid

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.