Evidence map›Paper›PMID 40137965›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2025

Insecticides and testicular health: mechanisms of injury and protective natural products.

Samar F Darwish, Yasser M Moustafa, Sherif S Abdel Mageed, Ghaneya S Hassan, Safwat Abdelhady Mangoura, Shaza H Aly, Mai A Mansour, Ahmed Amr Raouf, Al-Aliaa M Sallam, Sylvia F Fawzi and 7 more

Abstract readReview
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Samar F DarwishPharmacology and Toxicology Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Yasser M MoustafaPharmacology and Toxicology Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Sherif S Abdel MageedPharmacology and Toxicology Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Ghaneya S HassanPharmaceutical Chemistry Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Safwat Abdelhady MangouraPharmacology and Toxicology Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Shaza H AlyDepartment of Pharmacognosy, Faculty of Pharmacy, Badr University in Cairo, Cairo, 11829, Egypt.
Mai A MansourPharmaceutical Chemistry Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Ahmed Amr RaoufPharmacology and Toxicology Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Al-Aliaa M SallamDepartment of Biochemistry, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Sylvia F FawziPharmacology and Toxicology Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Asmaa M AttaPharmaceutical Chemistry Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Ola ElazazyDepartment of Biochemistry, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Walaa A El-DakrouryDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Aya A El-DemerdashPharmacology and Toxicology Department, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
El-Zahra M EsmatDepartment of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Mahmoud A ElrebehyDepartment of Biochemistry, Faculty of Pharmacy, Galala University, New Galala City, 43713, Suez, Egypt.
Ahmed S DoghishDepartment of Biochemistry, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt. ahmed_doghish@azhar.edu.eg.ORCID http://orcid.org/0000-0002-0136-7096

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In agriculture and public health, insecticides are vital chemicals that help manage diseases and control pests. However, their extensive use has raised concerns about their negative consequences on both humans and animals. Pesticide exposure impacts numerous human organs, including the reproductive system. Infertility is caused by reproductive system disorders, which is why they have received a lot of attention in recent decades. According to what is currently known, insecticides are among the substances that may lower the quality of the semen produced by exposed workers. The mechanisms of this action are still unclear, even though numerous underlying mechanisms have been suggested. With an emphasis on the harmful effects of insecticides on male reproductive processes, this review provides a thorough analysis of the toxicity profile of these substances. To reduce insecticides' negative impacts on human and animal health and to direct future research initiatives, it is essential to comprehend their harmful consequences.

Indexed as

Biological ProductsInfertility, MaleInsecticidesTestisAnimalsHumansMaleOccupational ExposureBiological ProductsInsecticidesEndocrine disruptionInsecticidesNatural productsPotential hazardsTesticular function

Identifiers

PMID40137965
PMCPMC12449350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.