Evidence map›Paper›PMID 40137919›Full record

ArticleToxins2025

Effects of a Multicomponent Mycotoxin Detoxifying Agent on Health and Performance of Weaned Pigs Under Combined Dietary Exposure to Deoxynivalenol (DON) and Zearalenone (ZEN).

Jog Raj, Panagiotis Tassis, Klaus Männer, Hunor Farkaš, Zdenka Jakovčević, Marko Vasiljević

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jog RajPatent Co, DOO., Vlade Ćetkovića 1A, 24211 Mišićevo, Serbia.ORCID 0000-0002-4408-255X
Panagiotis TassisFarm Animals Clinic, School of Veterinary Medicine, Aristotle University of Thessaloniki, 54627 Thessaloniki, Greece.ORCID 0000-0002-8879-4620
Klaus MännerInstitute of Animal Nutrition, Freie Universität Berlin, Königin-Luise-Str. 49, 14195 Berlin, Germany.
Hunor FarkašPatent Co, DOO., Vlade Ćetkovića 1A, 24211 Mišićevo, Serbia.
Zdenka JakovčevićPatent Co, DOO., Vlade Ćetkovića 1A, 24211 Mišićevo, Serbia.
Marko VasiljevićPatent Co, DOO., Vlade Ćetkovića 1A, 24211 Mišićevo, Serbia.

Funding

Patent Co DOO FA 03-23
6 · The paper itself

Abstract

The aim of the present study was to evaluate the efficacy of a multicomponent mycotoxin detoxifying agent (MMDA, MYCORAID, Patent Co, Mišićevo, Serbia) in weaned pigs receiving contaminated feed with deoxynivalenol (DON) and zearalenone (ZEN). In total, 168 pigs were equally allocated in four experimental groups from day 25 to day 66 of age. The T1 group received feed without mycotoxins or MMDA. The pigs in group T2 received contaminated feed (CF) with 1.5 mg of DON/kg feed and 0.9 mg of ZEN/kg feed for the first two weeks and 1.2 mg of DON/kg feed and 0.9 mg of ZEN/kg feed for the rest of the trial period, without the addition of MMDA. Groups T3 and T4 received the CF with the addition of 1.5 g of MMDA/kg feed (T3), or 3 g of MMDA/kg feed (T4). Performance parameters, stress, and inflammatory biomarkers, as well as mycotoxin residues in liver, kidney, and muscle tissue were assessed. The results demonstrated improved average daily gain (ADG) and feed conversion ratio (FCR) along with reduced DON residues in kidney samples in groups T3 and T4 when compared with the T2 group. Although a typical dose-response relationship was not present in all parameter alterations, the results of the study proved the efficacy of the test product with improved growth performance and reduced mycotoxins absorption under the concurrent DON and ZEN exposure conditions and supported its use as a mitigating tool against mycotoxicosis under field conditions.

Indexed as

Animal FeedDietary ExposureTrichothecenesZearalenoneAnimalsFood ContaminationKidneyLiverMaleSwineWeaningdeoxynivalenolTrichothecenesZearalenonedeoxynivalenoldetoxifying agenthealthinflammatory biomarkersmycotoxin residuesmycotoxinsweaned pigszearalenone

Identifiers

PMID40137919
PMCPMC11946165

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.