ArticleToxins2025
Occurrence of Co-Contamination and Interaction of Multi-Mycotoxins in Dairy Cow Feed in China.
Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Sulforaphane Alleviates Zearalenone-Induced Oxidative Stress in Bovine Mammary Epithelial Cells.Animals : an open access journal from MDPI · 2026Article
- Fungal Contamination of Dairy Feed and Major Mycotoxin Transfer: A Risk Evaluation for Animal Exposure and Health.Toxins · 2026Article
- Combined exposure to emergingFrontiers in toxicology · 2026Article
- Occurrence of mycotoxins in pastures and conserved forages in the Southeast region of Brazil.Mycotoxin research · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Co-contamination of multiple mycotoxins in feed has become one of the most important issues in the world. In this study, the characteristics and interactions of co-contamination among 15 mycotoxins were explored in dairy cow feed, including total mixed ration (TMR), silage, maize, and hay feed. The results showed that four dairy cow feeds were constantly contaminated with mycotoxins, including zearalenone (ZEN), fumonisins (FBs), deoxynivalenol (DON), ochratoxin A (OTA), T-2 toxin (T-2), and aflatoxins (AFs). The contamination level of each mycotoxin was low, but the probability of co-contamination by three or more mycotoxins in one sample was very high. Between DON and aflatoxin B2 (AFB2), between aflatoxin M1 (AFM1) and OTA, between FB2 and aflatoxin B1 (AFB1), between 15-acetyl-deoxynivalenol (15-ADON) and ZEN, and between fumonisin B1 (FB1) and fumonisin B3 (FB3), and between aflatoxin M2 (AFM2) and aflatoxin G2 (AFG2), there were significant and strong correlations. Among the four typical feed samples, the combinations DON + ZEN, DON + FB1, FB1 + ZEN, OTA + ZEN, DON + 3-acetyl-deoxynivalenol (3-ADON), 3-ADON + ZEN, T-2 + ZEN, fumonisin B2 (FB2) + ZEN, and DON + FB3 had higher interaction rates than the other combinations (≥43.75%). Our study not only reveals that co-contamination with multiple mycotoxins is relatively common in dairy cow feed but also highlights the significant correlations between various mycotoxins and assesses the likelihood of their interactions. These findings are crucial for ensuring feed safety and safeguarding animal health.
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