Evidence map›Paper›PMID 40137824›Full record

ReviewTropical medicine and infectious disease2025

Sensitivity of Immunodiagnostic Tests in Localized Versus Disseminated Tuberculosis-A Systematic Review of Individual Patient Data.

Michael Eisenhut, Shagun Shah, Ozge Kaba, Manolya Kara, Murat Sütçü, Kyoung-Ho Song, Hong Bin Kim, Maoshui Wang

Abstract readReview
In one paragraph

Review in Tropical medicine and infectious disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael EisenhutPaediatric Department, Luton & Dunstable University Hospital, Lewsey Road, Luton LU40DZ, UK.
Shagun ShahPaediatric Department, Luton & Dunstable University Hospital, Lewsey Road, Luton LU40DZ, UK.
Ozge KabaPediatric Infectious Diseases Department, Başakşehir Çam and Sakura City Hospital, 34480 Istanbul, Turkey.ORCID 0000-0002-8381-3255
Manolya KaraDepartment of Pediatric Infectious Diseases, School of Medicine, Yeditepe University, 34728 Istanbul, Turkey.
Murat SütçüDepartment of Pediatric Infectious Diseases, School of Medicine, İstinye University, Bahçeşehir Liv Training and Education Hospital, 34010 Istanbul, Turkey.ORCID 0000-0002-2078-9796
Kyoung-Ho SongDivision of Infectious Diseases, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam 13620, Republic of Korea.
Hong Bin KimDivision of Infectious Diseases, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam 13620, Republic of Korea.
Maoshui WangShandong Key Laboratory of Infectious Respiratory Disease, Jinan 250013, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our objective was to perform a systematic review of individual patient data comparing immunodiagnostic test sensitivity in patients with localized versus disseminated tuberculosis who are from high- and less-than-high-income countries. In a systematic review of individual patient data, we compared IGRA results and characteristics of patients with disseminated tuberculosis with IGRA results and characteristics of patients with localized tuberculosis. Data were extracted from Pubmed, EMBASE and the Cochrane Library, analyzed and presented following the PRISMA-IPD and STROBE statements. We identified 52 patients with localized and 105 with disseminated tuberculosis. Immunodiagnostic tests in localized tuberculosis from high-income countries were positive in 88.8% and in 67.3% of patients with disseminated tuberculosis (

Indexed as

interferon gamma release assaylymph node tuberculosismiliary tuberculosissensitivitytuberculous meningitis

Identifiers

PMID40137824
PMCPMC11946558

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.