Evidence map›Paper›PMID 40137542›Full record

ArticleToxics2025

Arsenic Exposure During Pregnancy and Childhood: Factors Explaining Changes over a Decade.

Paola Rubilar, Macarena Hirmas-Adauy, Mauricio Apablaza, Camila Awad, Xaviera Molina, María Pía Muñoz, Iris Delgado, Nicolás C Zanetta-Colombo, Carla Castillo-Laborde, María Isabel Matute and 6 more

Abstract read
In one paragraph

Article in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Paola RubilarCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.ORCID 0000-0003-3578-459X
Macarena Hirmas-AdauyCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.ORCID 0000-0002-0959-0946
Mauricio ApablazaFacultad de Gobierno, Universidad del Desarrollo, Santiago 7610658, Chile.
Camila AwadCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.ORCID 0000-0001-7143-6854
Xaviera MolinaCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.
María Pía MuñozPrograma de Epidemiología, Escuela de Salud Pública, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Iris DelgadoCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.
Nicolás C Zanetta-ColomboDepartment of Geography, South Asia Institute, Heidelberg University, 69120 Heidelberg, Germany.
Carla Castillo-LabordeCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.
María Isabel MatuteCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.
Mauricio A RetamalPrograma de Comunicación Celular en Cáncer, Instituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.ORCID 0000-0003-2562-6686
Andrea OleaCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.
Paulina PinoPrograma de Epidemiología, Escuela de Salud Pública, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Claudia GonzálezCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.
Cristóbal CarvajalCentro de Informática Biomédica, Instituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.ORCID 0000-0002-1712-7396
Verónica IglesiasPrograma de Epidemiología, Escuela de Salud Pública, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.

Funding

Agencia Nacional de Investigación y Desarrollo FONIS 22I0119
6 · The paper itself

Abstract

Arsenic chronic exposure, particularly in its inorganic form, represents a significant public health concern. This study was conducted in Arica, the northernmost city in the country, whose inhabitants have been exposed to inorganic arsenic both naturally through drinking water and anthropogenically due to a toxic waste disposal site. We explored changes in inorganic arsenic levels in a cohort of pregnant women and their children over a decade, identifying exposure trends and their determinants. We used data on arsenic exposure through maternal urine samples during pregnancy, collected by the Health Authority between 2013 and 2016 (measurement 1), and followed up with assessments of their children in 2023 (measurement 2). Temporal changes in inorganic arsenic concentration were analyzed using the Wilcoxon Signed-Rank test, and a mixed linear regression model was employed to determine which factors contributed to urinary inorganic arsenic levels. We did not observe significant differences in mean arsenic concentrations between the two-time points (

Indexed as

biomarkerenvironmental justiceexposure in childreninorganic arsenicprenatal exposurewater exposure

Identifiers

PMID40137542
PMCPMC11945348

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.