Evidence map›Paper›PMID 40137412›Full record

ReviewJournal of personalized medicine2025

Precision Surgery for Glioblastomas.

Stephen J Price, Jasmine G Hughes, Swati Jain, Caroline Kelly, Ioana Sederias, Francesca M Cozzi, Jawad Fares, Yonghao Li, Jasmine C Kennedy, Roxanne Mayrand and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of personalized medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stephen J PriceCambridge Brain Tumour Imaging Laboratory, Academic Neurosurgery Division, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.ORCID 0000-0002-7535-3009
Jasmine G HughesCambridge Brain Tumour Imaging Laboratory, Academic Neurosurgery Division, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
Swati JainCambridge Brain Tumour Imaging Laboratory, Academic Neurosurgery Division, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
Caroline KellyDepartment of Neuro-Oncology Outpatient Physiotherapy, Cambridge University Hospitals, Cambridge CB2 0QQ, UK.
Ioana SederiasCambridge Brain Tumour Imaging Laboratory, Academic Neurosurgery Division, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
Francesca M CozziCambridge Brain Tumour Imaging Laboratory, Academic Neurosurgery Division, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.ORCID 0000-0003-3299-0590
Jawad FaresCambridge Brain Tumour Imaging Laboratory, Academic Neurosurgery Division, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.ORCID 0000-0002-5368-8764
Yonghao LiCambridge Brain Tumour Imaging Laboratory, Academic Neurosurgery Division, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
Jasmine C KennedyCambridge Brain Tumour Imaging Laboratory, Academic Neurosurgery Division, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.ORCID 0000-0003-1178-5897
Roxanne MayrandCambridge Brain Tumour Imaging Laboratory, Academic Neurosurgery Division, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
Queenie Hoi Wing WongCambridge Brain Tumour Imaging Laboratory, Academic Neurosurgery Division, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.ORCID 0000-0003-3285-4812
Yizhou WanCambridge Brain Tumour Imaging Laboratory, Academic Neurosurgery Division, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.ORCID 0000-0002-3166-8711
Chao LiCambridge Brain Tumour Imaging Laboratory, Academic Neurosurgery Division, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.

Funding

National Institute for Health and Social Care Research CDF-2018-11-ST1-016
6 · The paper itself

Abstract

Glioblastomas are the most common primary malignant brain tumor. Most of the recent improvements their treatment are due to improvements in surgery. Although many would consider surgery as the most personalized treatment, the variation in resection between surgeons suggests there remains a need for objective measures to determine the best surgical treatment for individualizing therapy for glioblastoma. We propose applying a personalized medicine approach to improve outcomes for patients. We suggest looking at personalizing preoperative preparation, improving the resection target by understanding what needs removing and what ca not be removed, and better patient selection with personalized rehabilitation plans for all patients.

Indexed as

brain mappingglioblastomaprehabilitationrehabilitationsurgical resection

Identifiers

PMID40137412
PMCPMC11943082

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.