Evidence map›Paper›PMID 40137351›Full record

ArticleJournal of functional biomaterials2025

Cobalt-Incorporated Hydroxyapatite Conditioned Media Promotes In Vitro Scratch Wound Healing and Mesenchymal Stem Cell Migration.

Weerapat Leelasangsai, Krongrat Thummachot, Puttita Thammasarnsophon, Autcharaporn Srion, Jintamai Suwanprateeb, Somying Patntirapong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Weerapat LeelasangsaiDepartment of Implantology, Faculty of Dentistry, Thammasat University, Pathum Thani 12120, Thailand.ORCID 0009-0009-9211-1966
Krongrat ThummachotFaculty of Dentistry, Thammasat University, Pathum Thani 12120, Thailand.
Puttita ThammasarnsophonFaculty of Dentistry, Thammasat University, Pathum Thani 12120, Thailand.
Autcharaporn SrionBiofunctional Materials and Devices Research Group, National Metal and Materials Technology Center (MTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani 12120, Thailand.
Jintamai SuwanprateebBiofunctional Materials and Devices Research Group, National Metal and Materials Technology Center (MTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani 12120, Thailand.ORCID 0000-0002-5555-3927
Somying PatntirapongFaculty of Dentistry, Thammasat University, Pathum Thani 12120, Thailand.ORCID 0000-0001-7537-577X

Funding

Thailand Science Research and Innovation Fundamental Fund Fiscal year 2023, Contract No. TUFF 82/2566
6 · The paper itself

Abstract

Cell migration of mesenchymal stem cells (MSCs) is critical for bone healing and remodeling. Cobalt is a well-known hypoxia mimic, which can enhance MSC migration. Therefore, the objective of this study was to investigate the migratory response of MSCs to a developed cobalt-incorporated hydroxyapatite (HACo) material. HACo was fabricated by a simple ion exchange procedure at concentrations ranging from 40 to 8000 μM into disc shape. HACo discs were incubated in the media and conditioned media (CM; HACo

Indexed as

cell migrationcobalthydroxyapatitemesenchymal stem cellwound healing

Identifiers

PMID40137351
PMCPMC11942815

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.