Evidence map›Paper›PMID 40137303›Full record

ArticleMarine drugs2025

Synthesis and Biological Activity of Glycosyl Thiazolyl Disulfides Based on Thiacarpine, an Analogue of the Cytotoxic Alkaloid Polycarpine from the Ascidian

Dmitry N Pelageev, Yuri E Sabutski, Svetlana M Kovach, Nadezhda N Balaneva, Ekaterina S Menchinskaya, Ekaterina A Chingizova, Anna L Burylova, Victor Ph Anufriev

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dmitry N PelageevG. B. Elyakov Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.ORCID 0000-0002-8793-7511
Yuri E SabutskiG. B. Elyakov Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.ORCID 0000-0003-3815-6142
Svetlana M KovachInstitute of High Technologies and Advanced Materials, Far Eastern Federal University, Ajax Bay 10, Russky Island, Vladivostok 690922, Russia.
Nadezhda N BalanevaG. B. Elyakov Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.
Ekaterina S MenchinskayaG. B. Elyakov Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.
Ekaterina A ChingizovaG. B. Elyakov Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.ORCID 0000-0003-0093-5757
Anna L BurylovaG. B. Elyakov Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.
Victor Ph AnufrievG. B. Elyakov Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.

Funding

Russian Science Foundation 23-23-00357
6 · The paper itself

Abstract

Polycarpine, a diimidazolyl disulfan alkaloid isolated from the ascidian

Indexed as

AlkaloidsAntineoplastic AgentsDisulfidesThiazinesThiazolesUrochordataAnimalsAnti-Infective AgentsBiofilmsHeLa CellsHumansAlkaloidsAnti-Infective AgentsAntineoplastic AgentsDisulfidesThiazinesThiazolesantimicrobial activitybiofilm formationbis(2-amino-4-phenyl-5-thiazolyl)disulfidecytotoxic activityhemolysisPolycarpa auratapolycarpinethiacarpinethioglycosides

Identifiers

PMID40137303
PMCPMC11943723

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.