Evidence map›Paper›PMID 40137301›Full record

ArticleMarine drugs2025

Bioprospecting Marine Fungi from the Plastisphere: Osteogenic and Antiviral Activities of Fungal Extracts.

Matteo Florio Furno, Vincent Laizé, Irene Arduino, Giang Nam Pham, Federica Spina, Mohamed Mehiri, David Lembo, Paulo J Gavaia, Giovanna Cristina Varese

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Journal of fungi (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Matteo Florio FurnoDepartment of Life Sciences and Systems Biology, University of Turin, Mycotheca Universitatis Taurinensis (MUT), Viale Mattioli 25, 10125 Turin, Italy.ORCID 0000-0001-6483-3886
Vincent LaizéCentre of Marine Sciences, University of Algarve, 8005-139 Faro, Portugal.ORCID 0000-0001-9565-9198
Irene ArduinoDepartment of Clinical and Biological Sciences, University of Turin, Regione Gonzole, 10, Orbassano, 10043 Turin, Italy.ORCID 0000-0002-6600-670X
Giang Nam PhamMarine Natural Products Team, UMR 7272, Institut de Chimie de Nice, Université Côte d'Azur, CNRS, 06108 Nice, France.ORCID 0000-0001-5704-1813
Federica SpinaDepartment of Life Sciences and Systems Biology, University of Turin, Mycotheca Universitatis Taurinensis (MUT), Viale Mattioli 25, 10125 Turin, Italy.ORCID 0000-0002-2736-0570
Mohamed MehiriMarine Natural Products Team, UMR 7272, Institut de Chimie de Nice, Université Côte d'Azur, CNRS, 06108 Nice, France.
David LemboDepartment of Clinical and Biological Sciences, University of Turin, Regione Gonzole, 10, Orbassano, 10043 Turin, Italy.
Paulo J GavaiaCentre of Marine Sciences, University of Algarve, 8005-139 Faro, Portugal.ORCID 0000-0002-9582-1957
Giovanna Cristina VareseDepartment of Life Sciences and Systems Biology, University of Turin, Mycotheca Universitatis Taurinensis (MUT), Viale Mattioli 25, 10125 Turin, Italy.ORCID 0000-0002-1455-6208

Funding

financed by the Portuguese Foundation for Science and Technology through project LA/P/0101/2020 LA/P/0101/2020financed by the Portuguese Foundation for Science and Technology through projects UIDB/04326/2020 UIDB/04326/2020financed by the Portuguese Foundation for Science and Technology through projects UIDP/04326/2020 UIDP/04326/2020This research was funded by EU funding to D.L. within the MUR PNRR Extended Partnership In-itiative on Emerging Infectious Diseases PE00000007was financed by the operational programmes CRESC Algarve 2020 and COMPETE 2020 through project EM-BRC.PT ALG-01-0145-FEDER-022121
6 · The paper itself

Abstract

Marine microplastics (MPs) represent a novel ecological niche, populated by fungi with high potential for pharmaceutical discovery. This study explores the bioactivity of fungal strains isolated from MPs in Mediterranean sediments, focusing on their osteogenic and antiviral activities. Crude extracts prepared via solid-state and submerged-state fermentation were tested for their effects on extracellular matrix mineralization in vitro and bone growth in zebrafish larvae, and for their activity against the respiratory syncytial virus (RSV) and herpes simplex virus type 2 (HSV-2). Several extracts exhibited significant mineralogenic and osteogenic activities, with

Indexed as

Antiviral AgentsFungiOsteogenesisAnimalsAquatic OrganismsBioprospectingGeologic SedimentsHerpesvirus 2, HumanHumansRespiratory Syncytial VirusesZebrafishAntiviral AgentsAspergillus jenseniimicroplasticsplastispheresecondary metabolitesSmFSSF

Identifiers

PMID40137301
PMCPMC11944246

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.