Evidence map›Paper›PMID 40137298›Full record

ArticleMarine drugs2025

Exploring the Preventive Potential of Solubilized Sturgeon Oil on Acute Infection with Respiratory Viruses.

Seong Ok Park, Erdenebileg Uyangaa, Yong-Kwang Lee, Suk-Hyun Yun, Minyeong Yu, Hyo Jin Kim, Hye Won Cho, Hee Won Byeon, Chong-Kil Lee, Seong Kug Eo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Seong Ok ParkBio-Safety Research Institute, and Core Facility Center for Zoonosis Research (Core-FCZR), College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Republic of Korea.
Erdenebileg UyangaaBio-Safety Research Institute, and Core Facility Center for Zoonosis Research (Core-FCZR), College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Republic of Korea.
Yong-Kwang LeeBIO R&D Center, Sturgeon Bio Ltd., Co., Cheongju 28581, Republic of Korea.
Suk-Hyun YunBio-Safety Research Institute, and Core Facility Center for Zoonosis Research (Core-FCZR), College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Republic of Korea.
Minyeong YuBio-Safety Research Institute, and Core Facility Center for Zoonosis Research (Core-FCZR), College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Republic of Korea.
Hyo Jin KimBio-Safety Research Institute, and Core Facility Center for Zoonosis Research (Core-FCZR), College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Republic of Korea.
Hye Won ChoBio-Safety Research Institute, and Core Facility Center for Zoonosis Research (Core-FCZR), College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Republic of Korea.
Hee Won ByeonBio-Safety Research Institute, and Core Facility Center for Zoonosis Research (Core-FCZR), College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Republic of Korea.
Chong-Kil LeeBIO R&D Center, Sturgeon Bio Ltd., Co., Cheongju 28581, Republic of Korea.
Seong Kug EoBio-Safety Research Institute, and Core Facility Center for Zoonosis Research (Core-FCZR), College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Republic of Korea.

Funding

Korea Basic Science Institute 2021R1A6C101C369Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) HI22C0591National Research Foundation of Korea 2019R1A6A1A03033084
6 · The paper itself

Abstract

Acute respiratory viral infections (ARIs) represent a significant global health challenge, contributing heavily to worldwide morbidity and mortality rates. Recent efforts to combat ARIs have focused on developing nasal spray formulations that effectively target the nasal mucosa. However, challenges such as irritation, discomfort, and safety concerns highlight the need for natural, eco-friendly ingredients. In this study, we evaluated the efficacy of solubilized sturgeon oil (SSO), prepared as an oil-in-water nanoemulsion from Siberian sturgeon, as an eco-friendly preventive nasal spray agent against ARIs. Intranasal pre-treatment with SSO effectively inhibited respiratory infections caused by SARS-CoV-2, influenza A virus (IAV), and respiratory syncytial virus (RSV). Additionally, it suppressed viral replication in both nasal and lung tissues. This antiviral effect was linked to reduced pulmonary inflammation, characterized by decreased infiltration of Ly-6C

Indexed as

Antiviral AgentsFish OilsRespiratory Tract InfectionsAdministration, IntranasalAnimalsCOVID-19FishesHumansInfluenza A virusLungMiceNasal SpraysRespiratory Syncytial Virus InfectionsSARS-CoV-2Virus ReplicationAntiviral AgentsFish OilsNasal Spraysacute respiratory viral infectioninfluenza A virusrespiratory syncytial virusSARS-CoV-2solubilized sturgeon oil

Identifiers

PMID40137298
PMCPMC11943521

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.