Evidence map›Paper›PMID 40137283›Full record

ReviewMarine drugs2025

The Origin, Properties, Structure, Catalytic Mechanism, and Applications of Fucoidan-Degrading Enzymes.

Yi Zhao, Limin Ning, Penghui Zhu, Jinju Jiang, Zhong Yao, Benwei Zhu

Abstract readReview
In one paragraph

Review in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi ZhaoCollege of Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Limin NingCollege of Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Penghui ZhuCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.
Jinju JiangCollege of Food Engineering, Qingdao Institute of Technology, Qingdao 266300, China.
Zhong YaoCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.
Benwei ZhuCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.ORCID 0000-0001-5692-8535

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fucoidanase is a class of enzymes capable of hydrolyzing fucoidan, a complex sulfated polysaccharide found mainly in marine brown algae and some marine invertebrates. Fucoidan (FUC) has a wide range of potential health benefits and therapeutic effects, including antitumor, immunomodulatory, antiviral, and hypoglycemic activities. Fucoidanase can hydrolyze high-molecular-weight fucoidan into medium- and low-molecular-weight fucoidan. The low-molecular-weight fucoidan not only has good solubility, low viscosity, and high absorption rate but also retains the original biological activities of fucoidan. Fucoidanase has received much attention in recent years. This paper reviews the taxonomic origin, structure, enzymatic properties, and applications of fucoidanase to provide a reference for the study of fucoidanase.

Indexed as

Glycoside HydrolasesPolysaccharidesAnimalsAntineoplastic AgentsAquatic OrganismsHumansHydrolysisPhaeophyceaeAntineoplastic AgentsfucoidanGlycoside HydrolasesPolysaccharidesapplicationsfucoidanfucoidanasekinetic propertiesstructuresubstrate specificity

Identifiers

PMID40137283
PMCPMC11943901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.