Evidence map›Paper›PMID 40137150›Full record

ReviewMetabolites2025

Metatranscriptomics for Understanding the Microbiome in Food and Nutrition Science.

Christina F Butowski, Yash Dixit, Marlon M Reis, Chunlong Mu

Abstract readReview
In one paragraph

Review in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. International journal of molecular sciences · 2025
    Article
  14. Investigating the Microbial Dynamics ofFoods (Basel, Switzerland) · 2025
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christina F ButowskiSmart Foods and Bioproducts, AgResearch, Te Ohu Rangahau Kai, Palmerston North 4474, New Zealand.ORCID 0000-0002-3165-5988
Yash DixitSmart Foods and Bioproducts, AgResearch, Te Ohu Rangahau Kai, Palmerston North 4474, New Zealand.ORCID 0000-0002-7913-8437
Marlon M ReisSmart Foods and Bioproducts, AgResearch, Te Ohu Rangahau Kai, Palmerston North 4474, New Zealand.
Chunlong MuSmart Foods and Bioproducts, AgResearch, Te Ohu Rangahau Kai, Palmerston North 4474, New Zealand.

Funding

AgResearch Strategic Science Investment Fund PRJ0665467, PRJ0754138
6 · The paper itself

Abstract

Microbiome science has greatly expanded our understanding of the diverse composition and function of gut microorganisms over the past decades. With its rich microbial composition, the microbiome hosts numerous functionalities essential for metabolizing food ingredients and nutrients, resulting in the production of active metabolites that affect food fermentation or gut health. Most of these processes are mediated by microbial enzymes such as carbohydrate-active enzymes and amino acid metabolism enzymes. Metatranscriptomics enables the capture of active transcripts within the microbiome, providing invaluable functional insights into metabolic activities. Given the inter-kingdom complexity of the microbiome, metatranscriptomics could further elucidate the activities of fungi, archaea, and bacteriophages in the microbial ecosystem. Despite its potential, the application of metatranscriptomics in food and nutrition sciences remains limited but is growing. This review highlights the latest advances in food science (e.g., flavour formation and food enzymology) and nutrition science (e.g., dietary fibres, proteins, minerals, and probiotics), emphasizing the integration of metatranscriptomics with other technologies to address key research questions. Ultimately, metatranscriptomics represents a powerful tool for uncovering the microbiome activity, particularly in relation to active metabolic processes.

Indexed as

dietary fibresflavour formationfood fermentationmetatranscriptomicsmicrobiomenutrition

Identifiers

PMID40137150
PMCPMC11943699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.