Evidence map›Paper›PMID 40137036›Full record

ArticleMembranes2025

Enhanced Protein Separation Performance of Cellulose Acetate Membranes Modified with Covalent Organic Frameworks.

Shurui Shao, Maoyu Liu, Baifu Tao, Kayode Hassan Lasisi, Wenqiao Meng, Xing Wu, Kaisong Zhang

Abstract read
In one paragraph

Article in Membranes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shurui ShaoCollege of Environmental Science and Engineering, Ocean University of China, Qingdao 266100, China.
Maoyu LiuCollege of Environmental Science and Engineering, Ocean University of China, Qingdao 266100, China.
Baifu TaoCollege of Environmental Science and Engineering, Ocean University of China, Qingdao 266100, China.
Kayode Hassan LasisiCollege of Environmental Science and Engineering, Ocean University of China, Qingdao 266100, China.ORCID 0000-0003-1771-3325
Wenqiao MengKey Laboratory of Urban Pollutant Conversion, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China.
Xing WuCSIRO Manufacturing, Clayton South, VIC 3169, Australia.
Kaisong ZhangCollege of Environmental Science and Engineering, Ocean University of China, Qingdao 266100, China.

Funding

Ministry of Science and Technology of the People's Republic of China 2023YFC3700038
6 · The paper itself

Abstract

As a porous crystalline material, covalent organic frameworks (COFs) have attracted significant attention due to their extraordinary features, such as an ordered pore structure and excellent stability. Synthesized through the aldehyde amine condensation reaction, TpPa-1 COFs (Triformylphloroglucinol-p-Phenylenediamine-1 COFs) were blended with cellulose acetate (CA) to form a casting solution. The TpPa-1 COF/CA ultrafiltration membrane was then prepared using the non-solvent-induced phase inversion (NIPS) method. The influence of TpPa-1 COFs content on the hydrophilicity, stability and filtration performance of the modified membrane was studied. Due to the hydrophilic groups in TpPa-1 COFs and the network structure formed by covalent bonds, the modified CA membranes exhibited higher hydrophilicity and lower protein adsorption compared with the pristine CA membrane. The porous crystalline structure of TpPa-1 COFs increased the water permeation path in the CA membrane, improving the permeability of the modified membrane while maintaining an outstanding bovine serum albumin (BSA) rejection. Furthermore, the addition of TpPa-1 COFs reduced protein adsorption on the CA membrane and overcame the trade-off between permeability and selectivity in CA membrane bioseparation applications. This approach provides a sustainable method for enhancing membrane performance while enhancing the application of membranes in protein purification.

Indexed as

cellulose acetatecovalent organic frameworksprotein adsorptiontrade-offultrafiltration

Identifiers

PMID40137036
PMCPMC11944191

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.