Evidence map›Paper›PMID 40137031›Full record

ReviewMembranes2025

The Importance of Bilayer Asymmetry in Biological Membranes: Insights from Model Membranes.

Igor S Oliveira, Guilherme X Pinheiro, Maria Luana B Sa, Pedro Henrique L O Gurgel, Samuel U Pizzol, Rosangela Itri, Vera B Henriques, Thais A Enoki

Abstract readReview
In one paragraph

Review in Membranes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Igor S OliveiraInstitute of Physics, University of Sao Paulo, Sao Paulo 05508-090, Brazil.ORCID 0000-0003-4554-0505
Guilherme X PinheiroInstitute of Physics, University of Sao Paulo, Sao Paulo 05508-090, Brazil.
Maria Luana B SaInstitute of Physics, University of Sao Paulo, Sao Paulo 05508-090, Brazil.
Pedro Henrique L O GurgelInstitute of Physics, University of Sao Paulo, Sao Paulo 05508-090, Brazil.
Samuel U PizzolInstitute of Physics, University of Sao Paulo, Sao Paulo 05508-090, Brazil.
Rosangela ItriInstitute of Physics, University of Sao Paulo, Sao Paulo 05508-090, Brazil.ORCID 0000-0001-9311-0804
Vera B HenriquesInstitute of Physics, University of Sao Paulo, Sao Paulo 05508-090, Brazil.ORCID 0000-0002-0464-8168
Thais A EnokiInstitute of Physics, University of Sao Paulo, Sao Paulo 05508-090, Brazil.ORCID 0000-0003-4639-9160

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/04046-4Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/07024-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/05540-5Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/11908-5Fundação de Amparo à Pesquisa do Estado de São Paulo 2024/00346-9Fundação de Amparo à Pesquisa do Estado de São Paulo 2024/02663-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2024/14296-3Serrapilheira Institute R-2401-46767
6 · The paper itself

Abstract

This mini-review intends to highlight the importance of bilayer asymmetry. Biological membranes are complex structures that are a physical barrier separating the external environment from the cellular content. This complex bilayer comprises an extensive lipid repertory, suggesting that the different lipid structures might play a role in the membrane. Interestingly, this vast repertory of lipids is asymmetrically distributed between leaflets that form the lipid bilayer. Here, we discuss the properties of the plasma membrane from the perspective of experimental model membranes, consisting of simplified and controlled

Indexed as

asymmetric membraneslipid bilayerliquid ordered and liquid disordered phasespartition coefficient

Identifiers

PMID40137031
PMCPMC11943618

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.