Mind the Gap! Core-Peripheral Temperature Gradient and Its Relationship to Mortality in Major Burns.

Niamh Keohane, Jennifer Driver, Randeep Mullhi, Elizabeth Chipp, Barbara Torlinska, Tomasz Torlinski

Abstract read

In one paragraph

Article in European burn journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Niamh KeohaneWorcestershire Royal Hospital, Worcestershire Acute Hospitals NHS Trust, Worcester WR5 1DD, UK.ORCID 0009-0003-9490-9214

Jennifer DriverSouthmead Hospital, North Bristol NHS Trust, Bristol BS10 5NB, UK.

Randeep MullhiWest Midlands Burn Centre, Queen Elizabeth Hospital, University Hospitals Birmingham NHS FT, Birmingham B15 2GW, UK.ORCID 0000-0002-2387-7126

Elizabeth ChippWest Midlands Burn Centre, Queen Elizabeth Hospital, University Hospitals Birmingham NHS FT, Birmingham B15 2GW, UK.

Barbara TorlinskaDepartment of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham B15 2TT, UK.

Tomasz TorlinskiWest Midlands Burn Centre, Queen Elizabeth Hospital, University Hospitals Birmingham NHS FT, Birmingham B15 2GW, UK.ORCID 0000-0003-2255-5317

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between hypothermia and poor outcomes in severe burn injury is well established. However, the significance of the core-peripheral temperature gradient has not previously been investigated. Institutional guidance at our burns centre advocates avoiding hypothermia and targeting a body temperature between 37.5 and 39.5 °C. The core-peripheral temperature gap should be ≤2 °C, based on expert opinion. Data from 61 patients admitted to the Intensive Care Unit (ICU) with severe burns between 2016 and 2022 were analysed. A higher core temperature at 48 h, avoidance of hypothermia and a core-peripheral temperature gap > 2 °C were associated with reduced odds of mortality. The mean core body temperature and core-peripheral temperature gap increased over the first 48 h (r = 0.5,

Indexed as

body temperatureburncore-peripheral gapcore temperaturecritical careintensive caremortalityresuscitationthermal injurythermoregulation

Identifiers

PMID40137007

DOI10.3390/ebj6010011

PMCPMC11940914

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.