Evidence map›Paper›PMID 40136921›Full record

ReviewGels (Basel, Switzerland)2025

Hydrogel-Based Biomaterials: A Patent Landscape on Innovation Trends and Patterns.

Ahmed Fatimi, Fouad Damiri, Nada El Arrach, Houria Hemdani, Adina Magdalena Musuc, Mohammed Berrada

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ahmed FatimiChemical Science and Engineering Research Team (ERSIC), Department of Chemistry, Polydisciplinary Faculty of Beni Mellal (FPBM), Sultan Moulay Slimane University (USMS), P.O. Box 592, Mghila Campus, Beni Mellal 23000, Morocco.ORCID 0000-0001-8749-2009
Fouad DamiriLaboratory of Biology and Health, Faculty of Sciences Ben M'Sick, University Hassan II of Casablanca, Casablanca 20000, Morocco.ORCID 0000-0002-5478-8142
Nada El ArrachLaboratory of Biology and Health, Faculty of Sciences Ben M'Sick, University Hassan II of Casablanca, Casablanca 20000, Morocco.
Houria HemdaniLaboratory of Biology and Health, Faculty of Sciences Ben M'Sick, University Hassan II of Casablanca, Casablanca 20000, Morocco.
Adina Magdalena MusucInstitute of Physical Chemistry-Ilie Murgulescu, Romanian Academy, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0002-6935-8065
Mohammed BerradaLaboratory of Biology and Health, Faculty of Sciences Ben M'Sick, University Hassan II of Casablanca, Casablanca 20000, Morocco.ORCID 0000-0003-1809-2954

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hydrogel patent landscape is characterized by rapid growth and diverse applications, particularly in the biomedical field. Advances in material science, chemistry, novel manufacturing techniques, and a deeper understanding of biological systems have revolutionized the development of hydrogel-based biomaterials. These innovations have led to enhanced properties and expanded applications, particularly in regenerative medicine, drug delivery, and tissue engineering, positioning hydrogels as a pivotal material in the future of biomedical engineering. In this study, an updated patent landscape for hydrogel-based biomaterials is proposed. By analyzing patent documents, classifications, jurisdictions, and applicants, an overview is provided to characterize key trends and insights. The analysis reveals that hydrogel-related patents are experiencing significant growth, with a strong focus on biomedical applications. Foundational research in hydrogel formation remains dominant, with 96,987 patent documents highlighting advancements in crosslinking techniques, polysaccharide-based materials, and biologically active hydrogels for wound care and tissue regeneration. The United States and China lead in hydrogel-related patent filings, with notable contributions from Europe and a high number of international patents under the Patent Cooperation Treaty (PCT) system, reflecting the global interest in hydrogel technologies. Moreover, emerging innovations include biodegradable hydrogels designed for tissue regeneration, wearable hydrogel-based sensors, and advanced therapeutic applications such as chemoembolization agents and vascular defect treatments. The increasing integration of bioactive elements in hydrogel systems is driving the development of multifunctional biomaterials tailored to specific medical and environmental needs. While this study focuses on patent trends, the alignment between hydrogel research and patenting activities underscores the role of patents in bridging scientific discoveries with industrial applications. Future research could explore patent citation analysis and impact assessments to gain deeper insights into the technological significance of hydrogel-related inventions. Finally, a selection of the top 10 recent active and granted patents in the field of hydrogel-based biomaterials is presented as an illustrative example of innovation in this area and to illustrate cutting-edge innovations.

Indexed as

biomaterialshydrogelsinnovationpatent landscapepolymers

Identifiers

PMID40136921
PMCPMC11942307

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.