Evidence map›Paper›PMID 40136905›Full record

ArticleGels (Basel, Switzerland)2025

Effects of Polyhydroxybutyrate-co-hydroxyvalerate Microparticle Loading on Rheology, Microstructure, and Processability of Hydrogel-Based Inks for Bioprinted and Moulded Scaffolds.

Mercedes Pérez-Recalde, Evelina Pacheco, Beatriz Aráoz, Élida B Hermida

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mercedes Pérez-RecaldeInstituto de Tecnologías Emergentes y Ciencias Aplicadas (ITECA), National Scientific and Technical Research Council (CONICET), National University of General San Martin (UNSAM), San Martin 1650, Buenos Aires, Argentina.
Evelina PachecoEscuela de Ciencia y Tecnología, National University of General San Martin (UNSAM), San Martin 1650, Buenos Aires, Argentina.
Beatriz AráozInstituto de Tecnologías Emergentes y Ciencias Aplicadas (ITECA), National Scientific and Technical Research Council (CONICET), National University of General San Martin (UNSAM), San Martin 1650, Buenos Aires, Argentina.ORCID 0000-0003-3726-888X
Élida B HermidaInstituto de Tecnologías Emergentes y Ciencias Aplicadas (ITECA), National Scientific and Technical Research Council (CONICET), National University of General San Martin (UNSAM), San Martin 1650, Buenos Aires, Argentina.ORCID 0000-0002-6082-2693

Funding

Argentinian Ministry of Science, Technology and Productive Innovation (MINCyT) PICT 2020-SERIE A-02912National Scientific and Technical Research Council (CONICET) PIP-0437
6 · The paper itself

Abstract

Resorbable microparticles can be added to hydrogel-based biocompatible scaffolds to improve their mechanical characteristics and allow localised drug delivery, which will aid in tissue repair and regeneration. It is well-known that bioprinting is important for producing scaffolds personalised to patients by loading them with their own cells and printing them with specified shapes and dimensions. The question is how the addition of such particles affects the rheological responsiveness of the hydrogels (which is critical during the printing process) as well as mechanical parameters like the elastic modulus. This study tries to answer this question using a specific system: an alginate-gelatine hydrogel containing polyhydroxybutyrate-co-hydroxyvalerate (PHBV) microparticles. Scaffolds were made by bioprinting and moulding incorporating PHBV microspheres (7-12 μm in diameter) into alginate-gelatine inks (4.5 to 9.0%

Indexed as

alginate–gelatinebioprintinghydrogelmicrospherespolyhydroxyalkanoatestissue engineering

Identifiers

PMID40136905
PMCPMC11941948

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.