Evidence map›Paper›PMID 40136902›Full record

ArticleGels (Basel, Switzerland)2025

Ion-Specific Gelation and Internal Dynamics of Nanocellulose Biocompatible Hybrid Hydrogels: Insights from Fluctuation Analysis.

Arianna Bartolomei, Elvira D'Amato, Marina Scarpa, Greta Bergamaschi, Alessandro Gori, Paolo Bettotti

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arianna BartolomeiNanoscience Laboratory, Department of Physics, University of Trento, v. Sommarive 14, Povo, 38123 Trento, Italy.
Elvira D'AmatoNanoscience Laboratory, Department of Physics, University of Trento, v. Sommarive 14, Povo, 38123 Trento, Italy.
Marina ScarpaNanoscience Laboratory, Department of Physics, University of Trento, v. Sommarive 14, Povo, 38123 Trento, Italy.ORCID 0000-0001-8365-2706
Greta BergamaschiNational Research Council of Italy, Istituto di Chimica del Riconoscimento Molecolare (ICRM), Via Mario Bianco, 9, 20131 Milano, Italy.ORCID 0000-0002-4501-4057
Alessandro GoriNational Research Council of Italy, Istituto di Chimica del Riconoscimento Molecolare (ICRM), Via Mario Bianco, 9, 20131 Milano, Italy.ORCID 0000-0003-1640-7238
Paolo BettottiNanoscience Laboratory, Department of Physics, University of Trento, v. Sommarive 14, Povo, 38123 Trento, Italy.ORCID 0000-0001-9658-4167

Funding

European Union N.E53D2301787000, E53D2300513000
6 · The paper itself

Abstract

Hydrogels find widespread use in bioapplications for their ability to retain large amounts of water while maintaining structural integrity. In this article, we investigate hybrid hydrogels made of nanocellulose and either amino-polyethylenglycol or sodium alginates and we present two novel results: (1) the biocompatibility of the amino-containing hybrid gel synthesized using a simplified receipt does not require any intermediate synthetic step to functionalize either component and (2) the fluctuation in the second-order correlation function of a dynamic light scattering experiment provides relevant information about the characteristic internal dynamics of the materials across the entire sol-gel transition as well as quantitative information about the ion-specific gel formation. This novel approach offers significantly better temporal (tens of μs) and spatial (tens of μm) resolution than many other state-of-the-art techniques commonly used for such analyses (such as rheometry, SAXS, and NMR) and it might find widespread application in the characterization of nano- to microscale dynamics in soft materials.

Indexed as

cell culturedynamic light scatteringhydrogelsnanocellulosesol–gel transition

Identifiers

PMID40136902
PMCPMC11942523

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.