Evidence map›Paper›PMID 40136880›Full record

ArticleGels (Basel, Switzerland)2025

Functional Properties of Gelatin-Alginate Hydrogels for Use in Chronic Wound Healing Applications.

Olha Maikovych, Pamela Pasetto, Nataliia Nosova, Olena Kudina, Dmytro Ostapiv, Volodymyr Samaryk, Serhii Varvarenko

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Preparation and Investigation ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Olha MaikovychDepartment of Organic Chemistry, Lviv Polytechnic National University, 12 Bandera Str., 79013 Lviv, Ukraine.ORCID 0000-0002-5776-9924
Pamela PasettoInstitut des Molécules et Matériaux du Mans, Faculté des Sciences & Techniques, Le Mans Université, Avnue Olivier Messiaen, 72085 Le Mans, Cedex 09, France.ORCID 0000-0003-2209-8080
Nataliia NosovaDepartment of Organic Chemistry, Lviv Polytechnic National University, 12 Bandera Str., 79013 Lviv, Ukraine.
Olena KudinaCÚRAM Research Ireland Centre for Medical Devices, University of Galway, H92 W2TY Galway, Ireland.ORCID 0009-0000-9573-8064
Dmytro OstapivInstitute of Animal Biology NAAS, 38 V. Stusa Str., 79034 Lviv, Ukraine.
Volodymyr SamarykDepartment of Organic Chemistry, Lviv Polytechnic National University, 12 Bandera Str., 79013 Lviv, Ukraine.
Serhii VarvarenkoDepartment of Organic Chemistry, Lviv Polytechnic National University, 12 Bandera Str., 79013 Lviv, Ukraine.ORCID 0000-0001-7374-7787

Funding

National Research Foundation of Ukraine State registration number 0124U003832
6 · The paper itself

Abstract

In this study, a hydrogel material based on porcine gelatin and sodium alginate was synthesized for use as a dressing for chronic wound treatment. The hydrogels were covalently cross-linked using polyethylene glycol diglycidyl ether (PEGDE 500), and the interaction between the components was confirmed via FTIR. The properties of the resulting hydrogels were examined, including gel-fraction volume, swelling degree in different media, mechanical properties, pore size, cytotoxicity, and the ability to absorb and release analgesics (lidocaine, novocaine, sodium diclofenac). The hydrogel's resistance to enzymatic action by protease was enhanced both through chemical cross-linking and physical interactions between gelatin and alginate. The absorption capacity of the hydrogels, reaching 90 g per dm

Indexed as

crosslinkingdrug deliverygelatinhydrogelsodium alginatewound dressing

Identifiers

PMID40136880
PMCPMC11941921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.