Evidence map›Paper›PMID 40136752›Full record

ArticleDentistry journal2025

Identifying Key Factors in Papilla Growth Around Implants: Focus on Intraoral Negative Pressure.

Daniele Botticelli, Ivo Agabiti, Rihito Yamada, Nozomi Maniwa, Karol Alí Apaza Alccayhuaman, Yasushi Nakajima

Registry-linked trialAbstract read
In one paragraph

Article in Dentistry journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07204353 (A Novel Surgical Procedure for Peri-implant Papilla Reconstruction in the Aesthetic Region), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07204353 nacompletednot on this map

A Novel Surgical Procedure for Peri-implant Papilla Reconstruction in the Aesthetic Region: Modified Labial Pedicle Papilla Flap Technique With De-epithelialized Gingival Graft

TypeinterventionalSponsorCuneyt Asim AralRan2021 to 2025Enrolled80ConditionsPeri-Implant Papilla DeficiencyArmsPapilla-preserving incision (Control), Modified Labial Pedicle Papilla Flap (mLPPF), Modified Labial Pedicle Papilla Flap with De-epithelialized Gingival Graft (mLPPF+dGG)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniele BotticelliARDEC Academy, 47923 Rimini, Italy.ORCID 0000-0003-2804-1632
Ivo AgabitiARDEC Academy, 47923 Rimini, Italy.
Rihito YamadaDepartment of Oral Implantology, School of Dentistry, Osaka Dental University, 8-1 Kuzuhahanazonocho, Hirakata 573-1121, Osaka, Japan.
Nozomi ManiwaDepartment of Oral Implantology, School of Dentistry, Osaka Dental University, 8-1 Kuzuhahanazonocho, Hirakata 573-1121, Osaka, Japan.
Karol Alí Apaza AlccayhuamanARDEC Academy, 47923 Rimini, Italy.ORCID 0000-0003-4565-5222
Yasushi NakajimaARDEC Academy, 47923 Rimini, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The absence of interdental papillae in dental prosthetics often leads to unsatisfactory esthetic outcomes, such as black triangles and elongated clinical crowns. While previous research has demonstrated that papillae can regenerate in a coronal direction, the underlying mechanisms remain incompletely understood. Several theories have been proposed to explain this phenomenon, but no clear cause-effect relationship has been established among the various factors involved in spontaneous papilla growth around implants. This study aims to identify and classify the factors influencing this process. Various potential contributors were analyzed, including adjacent elements, buccal-lingual papilla width, contact point position, convergent neck design, crown overcontour, intraoral negative pressure, and others. To systematically organize these factors, a modified Overton Window and a mind map were employed. The factors were categorized as cause-related, essential, or influencing based on the collective opinion of the research group following a comprehensive review of the relevant literature. In the absence of clear evidence supporting a definitive cause-effect relationship, Occam's Razor (the principle of parsimony) was applied to identify the most plausible cause-related factors.

Indexed as

BOPTcrown overcontourimplantkeratinized tissuemucosa growthpapilla growthperi-implant mucosa

Identifiers

PMID40136752
PMCPMC11940915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.