Evidence map›Paper›PMID 40136687›Full record

ArticleCells2025

Long-Term Regulation of IL-17 Expression in Pacific Oyster Hemocytes by mGluR5 Through the Phosphoinositide Pathway.

Yiran Si, Deliang Li, Wenjing Ren, Xueshu Zhang, Lingling Wang, Linsheng Song

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yiran SiLiaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China.
Deliang LiLiaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China.
Wenjing RenLiaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China.
Xueshu ZhangLiaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China.ORCID 0000-0001-6473-5741
Lingling WangLiaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China.ORCID 0000-0002-1049-9170
Linsheng SongLiaoning Key Laboratory of Marine Animal Immunology & Disease Control, Dalian Ocean University, Dalian 116023, China.ORCID 0000-0002-3580-6560

Funding

Dalian High Level Talent Innovation Support Program 2022RG14Earmarked fund CARS-49National Natural Science Foundation of China 32230110National Natural Science Foundation of China 32373170Outstanding Talents and Innovative Team of Agricultural Scientific Research in MARASouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai) SML2023SP237Talented Scholars at Dalian Ocean University
6 · The paper itself

Abstract

Metabotropic glutamate receptor 5 (mGluR5) is a critical regulator of immune responses within the neuroimmune system, influencing cytokine secretion and immune cell function. Although extensively studied in mammals, its role in regulating IL-17 in invertebrate immunity is poorly understood. This study examines

Indexed as

CrassostreaHemocytesInterleukin-17PhosphatidylinositolsReceptor, Metabotropic Glutamate 5AnimalsApoptosisCalciumGlutamic AcidSignal TransductionVibrioCalciumGlutamic AcidInterleukin-17PhosphatidylinositolsReceptor, Metabotropic Glutamate 5Crassostrea gigasglutamatehemocyteIL-17 expressionmGluR5

Identifiers

PMID40136687
PMCPMC11941601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.