Evidence map›Paper›PMID 40136534›Full record

ArticleBiology2025

Epicardial Adipose Tissue in Arrhythmogenic Cardiomyopathy.

Davide Lapolla, Luca Canovi, Maria Letizia Berloni, Veronica Amantea, Cristina Balla, Federico Marchini, Evelina Faragasso, Matteo Bertini, Elisabetta Tonet

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Davide LapollaCardiology Unit, Azienda Ospedaliero Universitaria of Ferrara, 44124 FE, Italy.
Luca CanoviCardiology Unit, Azienda Ospedaliero Universitaria of Ferrara, 44124 FE, Italy.
Maria Letizia BerloniCardiology Unit, Azienda Ospedaliero Universitaria of Ferrara, 44124 FE, Italy.ORCID 0009-0002-2774-0853
Veronica AmanteaCardiology Unit, Azienda Ospedaliero Universitaria of Ferrara, 44124 FE, Italy.ORCID 0009-0002-5102-6887
Cristina BallaCardiology Unit, Azienda Ospedaliero Universitaria of Ferrara, 44124 FE, Italy.ORCID 0000-0003-2110-8961
Federico MarchiniCardiology Unit, Azienda Ospedaliero Universitaria of Ferrara, 44124 FE, Italy.ORCID 0000-0003-2622-4881
Evelina FaragassoDepartment of Cardiology and Cardiac Surgery, Cardiovascular Imaging, GVM Care&Research, 42121 Reggio Emilia, Italy.
Matteo BertiniCardiology Unit, Azienda Ospedaliero Universitaria of Ferrara, 44124 FE, Italy.ORCID 0000-0002-5285-7140
Elisabetta TonetCardiology Unit, Azienda Ospedaliero Universitaria of Ferrara, 44124 FE, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arrhythmogenic cardiomyopathy (ACM) is an inherited heart disease characterized by fibrofatty replacement of the ventricular myocardium, with an estimated prevalence of 1:5000 people in the general population. Sudden cardiac death is the first manifestation of this disease in 16-23% of patients with ACM. Fibrofatty infiltration can be identified with noninvasive cardiac magnetic resonance. Studies of epicardial fat deposits have suggested pathogenic roles of epicardial fats in mediating cardiac diseases and arrhythmias. Although myocardial fat infiltration has been well described in ACM, changes in epicardial fat deposits with this disease have not been well investigated. Our study shows that patients with ACM have a higher amount of EAT compared to controls. Additionally, the EAT amount seems to increase with the evolution of the disease.

Indexed as

arrhythmogenic cardiomyopathycardiac magnetic resonanceepicardial adipose tissue

Identifiers

PMID40136534
PMCPMC11939884

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.