Evidence map›Paper›PMID 40136465›Full record

ArticleCurrent issues in molecular biology2025

USP5 Suppresses Ferroptosis in Bladder Cancer Through Stabilization of GPX4.

Caiying Liu, Yanong Deng, Liang Huang, Xinrui Nie, Yuxuan Jiang, Xia Zhang, Huihui Zhang

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Caiying LiuSchool of Medical Technology and Translational Medicine, Hunan Normal University, 371 Tongzipo Road, Yuelu District, Changsha 410013, China.
Yanong DengSchool of Medical Technology and Translational Medicine, Hunan Normal University, 371 Tongzipo Road, Yuelu District, Changsha 410013, China.
Liang HuangSchool of Medical Technology and Translational Medicine, Hunan Normal University, 371 Tongzipo Road, Yuelu District, Changsha 410013, China.
Xinrui NieSchool of Medical Technology and Translational Medicine, Hunan Normal University, 371 Tongzipo Road, Yuelu District, Changsha 410013, China.
Yuxuan JiangSchool of Medical Technology and Translational Medicine, Hunan Normal University, 371 Tongzipo Road, Yuelu District, Changsha 410013, China.
Xia ZhangSchool of Medical Technology and Translational Medicine, Hunan Normal University, 371 Tongzipo Road, Yuelu District, Changsha 410013, China.ORCID 0009-0001-6229-4548
Huihui ZhangSchool of Medical Technology and Translational Medicine, Hunan Normal University, 371 Tongzipo Road, Yuelu District, Changsha 410013, China.ORCID 0000-0001-7691-5651

Funding

Hunan Province College Students Research Learning and Innovative Experiment Project S202310542202Hunan Provincial Health Commission Project 202202084830
6 · The paper itself

Abstract

USP5 has been proven to play an important role in the proliferation of bladder cancer (BC). In this study, we focused on investigating the molecular mechanism of ferroptosis induced by USP5 in bladder cancer. The role of USP5 in bladder cancer was evaluated using T24 wild-type cells (WT) and USP5 knockout (USP5

Indexed as

bladder cancerferroptosisGPX4USP5

Identifiers

PMID40136465
PMCPMC11941033

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.