Evidence map›Paper›PMID 40136398›Full record

ReviewCurrent issues in molecular biology2025

Recent Advances in the Isolation Strategies of Plant-Derived Exosomes and Their Therapeutic Applications.

Jeong-Geon Mun, Dong-Ha Song, Ji-Ye Kee, Yohan Han

Abstract readReview
In one paragraph

Review in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
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  10. International journal of nanomedicine · 2026
    Article
  11. Review
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  14. Review
  15. Exosome-like Nanoparticles Extracted from Plant Cells for Diabetes Therapy.International journal of molecular sciences · 2025
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Emerging Role of Plant-Derived Nanostructures in Nanomedicine.International journal of nanomedicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeong-Geon MunDepartment of Oriental Pharmacy, College of Pharmacy, Wonkwang-Oriental Medicines Research Institute, Wonkwang University, 460 Iksandae-ro, Iksan 54538, Jeonbuk, Republic of Korea.
Dong-Ha SongDepartment of Microbiology, Wonkwang University School of Medicine, Wonkwang University, 460 Iksandae-ro, Iksan 54538, Jeonbuk, Republic of Korea.
Ji-Ye KeeDepartment of Oriental Pharmacy, College of Pharmacy, Wonkwang-Oriental Medicines Research Institute, Wonkwang University, 460 Iksandae-ro, Iksan 54538, Jeonbuk, Republic of Korea.ORCID 0000-0002-9836-2127
Yohan HanDepartment of Microbiology, Wonkwang University School of Medicine, Wonkwang University, 460 Iksandae-ro, Iksan 54538, Jeonbuk, Republic of Korea.

Funding

Wonkwang University 2024
6 · The paper itself

Abstract

Exosome-like nanovesicles (ELNs) derived from natural products are gaining attention as innovative therapeutic agents due to their biocompatibility, low immunogenicity, and capability to transport bioactive molecules such as proteins, lipids, and nucleic acids. These plant-derived ELNs exhibit structural similarities with mammalian exosomes, making them suitable for drug delivery, microbiome-targeted therapies, and regenerative medicine. Recent studies highlight their potential in treating cancer, inflammation, and metabolic disorders. Additionally, ELNs have applications in cosmetics, agriculture, and the food industry. This review combines the latest advancements in research on plant-derived ELNs, focusing on isolation techniques, pharmacological effects, and therapeutic applications. Although plant-derived ELNs offer promising opportunities, several challenges must be addressed, including standardization, large-scale production, and in vivo efficacy. By summarizing cutting-edge studies and suggesting future directions, we aim to inspire further development of plant-derived ELNs as next-generation therapeutic platforms.

Indexed as

density gradient centrifugationdrug deliveryplant-derived exosome-like nanovesiclespolymer-based precipitationsize-exclusion chromatographyultracentrifuge

Identifiers

PMID40136398
PMCPMC11941663

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.