Evidence map›Paper›PMID 40136318›Full record

ReviewDermatopathology (Basel, Switzerland)2025

Hypertrophic Lichen Planus and Hypertrophic Skin Lesions Associated with Histological Lichenoid Infiltrate: A Case Report and Literature Review.

Biagio Scotti, Cosimo Misciali, Federico Bardazzi, Bianca Maria Piraccini, Michelangelo La Placa

Abstract readReview
In one paragraph

Review in Dermatopathology (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Scalp Biopsies for Alopecia.Dermatopathology (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Plantar Lichen Planus.Clinical case reports · 2026
    Article
  4. Review
  5. Rupioid Porokeratosis on the Lower Leg: An Unprecedented Case Report.Clinical, cosmetic and investigational dermatology · 2026
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Biagio ScottiDermatology Unit, IRCCS Azienda-Ospedaliero Universitaria di Bologna, 33-40126 Bologna, Italy.
Cosimo MiscialiDermatology Unit, IRCCS Azienda-Ospedaliero Universitaria di Bologna, 33-40126 Bologna, Italy.
Federico BardazziDermatology Unit, IRCCS Azienda-Ospedaliero Universitaria di Bologna, 33-40126 Bologna, Italy.ORCID 0000-0001-6162-2004
Bianca Maria PiracciniDermatology Unit, IRCCS Azienda-Ospedaliero Universitaria di Bologna, 33-40126 Bologna, Italy.ORCID 0000-0001-6537-9689
Michelangelo La PlacaDermatology Unit, IRCCS Azienda-Ospedaliero Universitaria di Bologna, 33-40126 Bologna, Italy.ORCID 0000-0002-6894-3350

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertrophic lichen planus (HLP) is a chronic inflammatory skin condition defined by verrucous, pruritic, papules and plaques usually affecting the lower limbs. The diagnosis of HLP is primarily clinical. However, due to its feasible generalized presentation and similarities with other hypertrophic cutaneous disorders, histological evaluation is often necessary. Many dermatological conditions that present with a hypertrophic clinical appearance can arise from a histological lichenoid infiltrate (HCLI). Hence, we provide an overview of the clinical, histopathological, and prognostic features of selected HCLI, including HLP, hypertrophic lichenoid dermatitis, hypertrophic lichen sclerosus (HLS), lichen simplex chronicus (LSC), squamous cell carcinoma (SCC), keratoacanthoma (KA), pseudoepitheliomatous hyperplasia (PEH), viral warts, and lupus erythematosus/lichen planus (LE/LP) overlap. Choosing the appropriate procedure and the anatomical site for an incisional biopsy requires thoughtful consideration to ensure sufficient depth and improve diagnostic accuracy by identifying the histological features specific to each hypertrophic condition.

Indexed as

histologyhistopathologyHLPHPVhypertrophic lichenoid dermatitishypertrophic lichen planushypertrophic lichen sclerosusLE/LP overlaplichen simplex chronicuslupus erythematosus/lichen planus overlap syndromepseudoepitheliomatous hyperplasiasquamous cell carcinomaviral wart

Identifiers

PMID40136318
PMCPMC11941438

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.