Evidence map›Paper›PMID 40136240›Full record

ArticleArquivos brasileiros de cardiologia2025

Atrial Fibrillation Catheter Ablation: Electroporation Against High-Power Short Duration Radiofrequency.

Rita Reis Santos, Rita Amador, Pedro Galvão Santos, Daniel Matos, Gustavo Rodrigues, João Carmo, Francisco Costa, Pedro Carmo, Francisco Morgado, Diogo Cavaco and 2 more

Abstract readComparative Study
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rita Reis SantosCentro Hospitalar de Lisboa Ocidental Hospital de Santa Cruz, Carnaxide, Lisboa - Portugal.ORCID 0000-0002-0881-053X
Rita AmadorCentro Hospitalar de Lisboa Ocidental Hospital de Santa Cruz, Carnaxide, Lisboa - Portugal.
Pedro Galvão SantosCentro Hospitalar de Lisboa Ocidental Hospital de Santa Cruz, Carnaxide, Lisboa - Portugal.
Daniel MatosCentro Hospitalar de Lisboa Ocidental Hospital de Santa Cruz, Carnaxide, Lisboa - Portugal.ORCID 0000-0002-1554-6116
Gustavo RodriguesCentro Hospitalar de Lisboa Ocidental Hospital de Santa Cruz, Carnaxide, Lisboa - Portugal.
João CarmoCentro Hospitalar de Lisboa Ocidental Hospital de Santa Cruz, Carnaxide, Lisboa - Portugal.
Francisco CostaCentro Hospitalar de Lisboa Ocidental Hospital de Santa Cruz, Carnaxide, Lisboa - Portugal.
Pedro CarmoCentro Hospitalar de Lisboa Ocidental Hospital de Santa Cruz, Carnaxide, Lisboa - Portugal.
Francisco MorgadoCentro Hospitalar de Lisboa Ocidental Hospital de Santa Cruz, Carnaxide, Lisboa - Portugal.
Diogo CavacoCentro Hospitalar de Lisboa Ocidental Hospital de Santa Cruz, Carnaxide, Lisboa - Portugal.ORCID 0000-0003-2771-345X
Mauricio ScanavaccaInstituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP - Brasil.ORCID 0000-0001-7327-2275
Pedro AdragãoCentro Hospitalar de Lisboa Ocidental Hospital de Santa Cruz, Carnaxide, Lisboa - Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary vein isolation (PVI) is crucial in treating symptomatic atrial fibrillation (AF). New ablation technologies, such as pulse-field ablation (PFA) and high-power short-duration (HPSD) have emerged in the electrophysiology lab. However, no study has compared the outcomes of these approaches.

objectiveTo compare the efficacy and safety of PFA and HPSD in AF symptomatic patients.

methodsSingle-centre, retrospective study of consecutive patients undergoing PVI with PFA or HPSD between May and December 2022. Demographic data, procedural data, and AF recurrence beyond the blanking period, were analysed. Comparative analysis between both techniques was performed. A P-value of <0.05 was considered statistically significant.

resultsA total 101 patients were included (61±11 years, 75% men); 56% of patients had paroxysmal AF and 19% underwent a redo ablation. Forty-five percent of patients underwent HPSD ablation and 55% PFA. Comparing HPSD and PFA, HPSD had a lower fluoroscopy time (5min [IQR 3-7min]vs 13min [IQR 10-16min], p<0.001), but higher procedure time (97min [IQR 75-142]vs 88min [IQR 66-111], p=0.13). Posterior wall isolation (PWI) was performed in 5 (11%) HPSD vs 20 (36%) PFA patients (p=0.004). There was only one case of major complication, a patient with cardiac tamponade following PFA, who was treated with pericardiocentesis. Over 384 (IQR 341 -545) days of follow-up, 76 patients (75%) were in sinus rhythm, while 25% of patients had AF recurrence: 10 PFA patients and 15 HPSD patients (p=0.06).

conclusionsBoth PFA and HPSD were found to be feasible and safe procedures. PFA resulted in shorter procedure times, and lower AF recurrence rates, mainly when PWI was performed. Although analysis in a real-world scenario is still scarce, both techniques seem to be efficient, with a low AF recurrence rate.

Indexed as

Atrial FibrillationCatheter AblationElectroporationAgedFemaleFluoroscopyHumansMaleMiddle AgedOperative TimePulmonary VeinsRecurrenceRetrospective StudiesTime FactorsTreatment Outcome

Identifiers

PMID40136240
PMCPMC12080718

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.