Evidence map›Paper›PMID 40135969›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2025

THE EFFECT OF PARTNER DELIVERY OF HIV SELF-TEST KITS ON HIV TESTING AND LINKAGE TO CARE IN PUBLIC CLINICS IN KENYA.

Catherine Kiptinness, Nelly Mugo, Kenneth K Mugwanya, Kenneth Ngure, Paul Mwangi, Dominic M Githuku Dip, Njeri Wairimu, Alfred Osoti, Marianne Mureithi, Renee Heffron

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Catherine KiptinnessDepartment of Global and Public Health, University of Nairobi, Nairobi, Kenya.ORCID 0000-0002-2647-0196
Nelly MugoPartners in Health Research and Development, Center for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Kenneth K MugwanyaDepartment of Global Health, University of Washington, Seattle, USA.
Kenneth NgureDepartment of Global Health, University of Washington, Seattle, USA.
Paul MwangiPartners in Health Research and Development, Center for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Dominic M Githuku DipPartners in Health Research and Development, Center for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Njeri WairimuPartners in Health Research and Development, Center for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya.
Alfred OsotiDepartment of Obstetrics and Gynaecology, University of Nairobi, Nairobi, Kenya.
Marianne MureithiDepartment of Medical Microbiology and Immunology, University of Nairobi, Nairobi, Kenya.
Renee HeffronDepartment of Medicine, University of Alabama at Birmingham, Alabama, USA.

Funding

Promoting Diversity, Equity, and Inclusivity in Research Training to Optimize HIV Prevention and TreatmentD43TW009580 · FIC · UNIVERSITY OF WASHINGTON · PI CAREY FARQUHAR, John Kinuthia · 2013 to 2026
$4.8M
Mentoring and research to prepare oral PrEP delivery platforms for novel HIVprevention productsK24MH123371 · NIMH · UNIVERSITY OF WASHINGTON · PI HEFFRON, RENEE A. · 2021 to 2025
$749k
A differentiated care model to improve the efficiency of PrEP delivery in KenyaR00MH118134 · NIMH · UNIVERSITY OF WASHINGTON · PI MUGWANYA, KENNETH KIGGUNDU · 2019 to 2021
$743k
FIC NIH HHS D43 TW009580NIMH NIH HHS K24 MH123371NIMH NIH HHS R00 MH118134
6 · The paper itself

Abstract

backgroundPartners of people living with HIV (PLHIV) at high risk of HIV acquisition are a target population who may benefit from innovative HIV testing strategies. We explored the effectiveness of the secondary distribution of HIVST kits by PLHIV enrolled in HIV care to catalyze testing and linkage to care.

methodsA prospective interventional study was conducted at four Kenyan HIV clinics deploying two testing strategies sequentially to reach sexual partners of PLHIV: 1) invitation by PLHIV for clinic-based testing and 2) distribution of HIVST kits by PLHIV. PLHIV were newly diagnosed with HIV or had been using antiretroviral therapy (ART) for <6 months or were not virally suppressed, with a sexual partner of unknown HIV status or whose sexual partner had tested >3 months ago. In-person interviewer-administered surveys were conducted with partners to determine whether they completed HIV testing and were linked to any follow-up care.

resultsA total of 345 PLHIV (167 invitation and 178 HIVST) and 274 (79.4%) of their sexual partners (135 invitation and 139 HIVST) were enrolled. Partners were more likely to get tested (98.6% vs. 77.8%, PPR=1.27, 95% CI [1.16- 1.39]) and to link to care (71.9% vs. 50.3%, PPR=1.43, 95% CI [1.17 - 1.74]) during the HIVST phase compared to the clinic phase. Among the subset of partners who tested HIV-positive, all were linked to care.

conclusionHIVST delivery by PLHIV increased the frequency of HIV testing and linkage to care among their partners. This strategy warrants further investigation to determine its potential for scale-up.

Identifiers

PMID40135969
PMCPMC12445175

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.