Evidence map›Paper›PMID 40135931›Full record

ArticlemBio2025

RIG-I and cGAS mediate antimicrobial and inflammatory responses of primary osteoblasts and osteoclasts to

Erin L Mills, Samantha R Suptela, Mary-Kate Key, Ian Marriott, M Brittany Johnson

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Osteomyelitis.Nature reviews. Disease primers · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erin L MillsDepartment of Biological Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina, USA.ORCID 0009-0004-5600-4999
Samantha R SuptelaDepartment of Biological Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina, USA.
Mary-Kate KeyGraduate Division of Biological and Biomedical Sciences, Emory University, Atlanta, Georgia, USA.
Ian MarriottDepartment of Biological Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina, USA.ORCID 0000-0002-4005-3487
M Brittany JohnsonDepartment of Biological Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina, USA.ORCID 0000-0003-4682-1827

Funding

Substance P exacerbation of staphylococcal bone damageR01AI170012 · NIAID · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI Morgan Brittany Johnson, Ian Marriott · 2022 to 2026
$1.9M
Type I interferon responses of bone cells to Staphylococcus aureus: A pilot studyR03AI176300 · NIAID · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI MARRIOTT, IAN · 2024 to 2025
$143k
NIAID NIH HHS R01 AI170012NIAID NIH HHS R03 AI176300NIH HHS R01 AI170012NIH HHS R01 AI170012, R03 AI176300
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DEAD Box Protein 58NucleotidyltransferasesOsteoblastsOsteoclastsStaphylococcus aureusAnimalsCells, CulturedCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseCytokinesHumansMiceMice, Inbred C57BLReceptors, ImmunologicStaphylococcal InfectionscGAS protein, humancGAS protein, mouseCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseCytokinesDdx58 protein, mouseDEAD Box Protein 58NucleotidyltransferasesReceptors, ImmunologicRIGI protein, humancGAScytokinesosteoblastsosteoclastsRIG-IStaphylococcus aureustype I interferon

Identifiers

PMID40135931
PMCPMC12077190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.