Evidence map›Paper›PMID 40135895›Full record

ArticleJournal of virology2025

Abortive PDCoV infection triggers Wnt/β-catenin pathway activation, enhancing intestinal stem cell self-renewal and promoting chicken resistance.

Shuai Zhang, Yanan Cao, Yanjie Huang, Xueli Zhang, Chunxiao Mou, Tao Qin, Zhenhai Chen, Wenbin Bao

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shuai Zhang *College of Animal Science and Technology, Yangzhou University, Yangzhou, China.ORCID 0000-0001-8507-3492
Yanan Cao *College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Yanjie HuangCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Xueli ZhangCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Chunxiao MouCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Tao QinCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Zhenhai ChenCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.ORCID 0000-0002-6704-7546
Wenbin BaoCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.ORCID 0000-0001-5486-2253

Funding

Graduate Research and Innovation Projects of Jiangsu Province KYCX24_3805National Key Research and Development Program of China 2023YFF1000900National Science Foundation For Young Scientists of China 32402729Natural Science Foundation of Jiangsu Province BK20220581Priority Academic Program Development of Jiangsu Higher Education Institutions NA
6 · The paper itself

Abstract

Porcine deltacoronavirus (PDCoV) is an emerging coronavirus causing economic losses to swine industries worldwide. PDCoV can infect chickens under laboratory conditions, usually with no symptoms or mild symptoms, and may cause outbreaks in backyard poultry and wildfowl, posing a potential risk of significant economic loss to the commercial poultry industry. However, the reasons for such a subdued reaction after infection are not known. Here, using chicken intestinal organoid monolayers, we found that although PDCoV infects them nearly as well as porcine intestinal organoid monolayers, infection did not result in detectable amounts of progeny virus. In

Indexed as

Cell Self RenewalCoronavirus InfectionsPoultry DiseasesStem CellsWnt Signaling PathwayAnimalsbeta CateninChickensGoblet CellsIntestinal MucosaIntestinesOrganoidsSwinebeta Cateninabortive infectionchickenintestinal barrierintestinal organoidsintestinal stem cellsPDCoVpigWnt/β-catenin signaling pathway

Identifiers

PMID40135895
PMCPMC11998530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.