Evidence map›Paper›PMID 40135802›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies.

Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fan XuDepartment of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 274 Zhijiang Road, Shanghai, 200071, China.
Yao LiuDepartment of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 274 Zhijiang Road, Shanghai, 200071, China.
Zujun QueResearch Center for Cancer, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 274 Zhijiang Road, Shanghai, 200071, China.
Bin LuoDepartment of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 274 Zhijiang Road, Shanghai, 200071, China.
Yun YangDepartment of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 274 Zhijiang Road, Shanghai, 200071, China.
Yan LiDepartment of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 274 Zhijiang Road, Shanghai, 200071, China.
Zhanxia ZhangCancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 725 Wanping South Road, Shanghai, 200032, China.ORCID https://orcid.org/0000-0002-0013-7221
Jianhui TianDepartment of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, 274 Zhijiang Road, Shanghai, 200071, China.

Funding

National Natural Science Foundation of China 82174245Shanghai Frontier Research Base of Disease and Syndrome Biology of Inflammatory Cancer Transformation 2021KJ03-12Shanghai Municipal Health Leading Talents Program 2022LJ014Shanghai Science and Technology Innovation Biomedical Science and Technology Support Project 22S11900800Traditional Chinese Medicine Science and Technology Development Project of Shanghai Medical Innovation & Development Foundation WL-HBRC-2021001KTraditional Chinese Medicine Science and Technology Development Project of Shanghai Medical Innovation & Development Foundation WL-XJRY-2021002K
6 · The paper itself

Abstract

Metastasis is the leading cause of death in patients with lung cancer. Multidisciplinary comprehensive treatments (MDT), including surgery, chemotherapy, radiotherapy, gene-targeted therapy, immunotherapy, antibody-drug conjugate (ADC), natural products, etc., have been currently used for lung cancer metastasis. The MDT model has shown promising efficacy against lung cancer metastasis in clinical practice. However, these therapies have some limitations, such as unusual toxic side effects, drug resistance, limited indications, and high costs. Therefore, emerging technological platforms are imperative to overcome these bottlenecks. Nanomedicine can be used to prepare efficient drug delivery systems owing to its good biocompatibility, high targeting, responsive release, and multidrug codelivery and plays an important role in the synergistic antimetastasis of lung cancer because of the optical, acoustic, electrical, thermal, and magnetic functions. This comprehensive review analyses the limitations of the MDT model, briefly outlines the advantages of nanotechnology, introduces the promising nanodrug delivery systems, summarizes the emerging nanostrategies against lung cancer metastasis based on the invasion-metastasis cascade process, and provides a summary of the prospects and challenges for the clinical translation of nanomedicines.

Indexed as

Drug Delivery SystemsLung NeoplasmsNanomedicineNeoplasm MetastasisAnimalsHumansclinical translationlung cancermetastasisnanodrug delivery systemsnanostrategiesthe invasion‐metastasis cascade process

Identifiers

PMID40135802
PMCPMC12199418

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.