Evidence map›Paper›PMID 40135799›Full record

ArticleJournal of medicinal chemistry2025

Development of [

Christian Lis, Friedrich-Alexander Ludwig, Steffen Fischer, Martin Ullrich, Hans-Joachim Lankau, Wiebke Sihver, Daniel Gündel, Desna Joseph, Christoph Meyer, Klaus Kopka and 3 more

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Christian LisABX Advanced Biochemical Compounds GmbH, Heinrich-Gläser-Straße 10-14, 01454 Radeberg, Germany.
Friedrich-Alexander LudwigInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Bautzner Landstraße 400, 01328 Dresden, Germany.ORCID 0000-0002-4358-5171
Steffen FischerInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Bautzner Landstraße 400, 01328 Dresden, Germany.
Martin UllrichInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Bautzner Landstraße 400, 01328 Dresden, Germany.
Hans-Joachim LankauABX Advanced Biochemical Compounds GmbH, Heinrich-Gläser-Straße 10-14, 01454 Radeberg, Germany.
Wiebke SihverInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Bautzner Landstraße 400, 01328 Dresden, Germany.ORCID 0000-0002-2876-9925
Daniel GündelInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Bautzner Landstraße 400, 01328 Dresden, Germany.ORCID 0000-0001-9743-2325
Desna JosephABX Advanced Biochemical Compounds GmbH, Heinrich-Gläser-Straße 10-14, 01454 Radeberg, Germany.
Christoph MeyerABX Advanced Biochemical Compounds GmbH, Heinrich-Gläser-Straße 10-14, 01454 Radeberg, Germany.
Klaus KopkaInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Bautzner Landstraße 400, 01328 Dresden, Germany.
Jens PietzschInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Bautzner Landstraße 400, 01328 Dresden, Germany.ORCID 0000-0002-1610-1493
Peter BrustInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Bautzner Landstraße 400, 01328 Dresden, Germany.
Alexander HoeppingABX Advanced Biochemical Compounds GmbH, Heinrich-Gläser-Straße 10-14, 01454 Radeberg, Germany.ORCID 0009-0008-4768-9593

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A current global limitation to the timely and equitable patient access to PSMA-based therapies for prostate cancer (PCa) is the insufficient PET capacity for pretreatment imaging. However, the extensive global availability of SPECT cameras renders this imaging technology as an attractive alternative. The lack of regulatory approved PSMA radioligands for SPECT imaging of PCa prompted us to design new

Indexed as

Antigens, SurfaceGlutamate Carboxypeptidase IIOrganotechnetium CompoundsProstatic NeoplasmsRadiopharmaceuticalsTechnetiumTomography, Emission-Computed, Single-PhotonAnimalsCell Line, TumorDrug DesignGallium RadioisotopesHumansLigandsMaleMiceTissue DistributionAntigens, SurfaceFOLH1 protein, humanGallium-68Gallium RadioisotopesGlutamate Carboxypeptidase IILigandsOrganotechnetium CompoundsRadiopharmaceuticalsTechnetium

Identifiers

PMID40135799
PMCPMC11997996

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.