Evidence map›Paper›PMID 40135781›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Self-Propelled In Situ Polymerized Nanoparticles Activating the STING Pathway for Enhanced Bladder Cancer Immunotherapy.

Lei Peng, Anguo Zhao, Rongkang Li, Yujun Liu, Daitian Tang, Dashi Deng, Qi Zhuang, Rui Liang, Shaohua Zhang, Song Wu

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lei PengDepartment of Urology, Lanzhou University Second Hospital, Lanzhou, 730000, P. R. China.ORCID https://orcid.org/0009-0002-3171-3137
Anguo ZhaoDepartment of Urology, South China Hospital, Medical School, Shenzhen University, Shenzhen, 518116, P. R. China.
Rongkang LiDepartment of Urology, Lanzhou University Second Hospital, Lanzhou, 730000, P. R. China.
Yujun LiuDepartment of Urology, South China Hospital, Medical School, Shenzhen University, Shenzhen, 518116, P. R. China.
Daitian TangDepartment of Urology, South China Hospital, Medical School, Shenzhen University, Shenzhen, 518116, P. R. China.
Dashi DengDepartment of Urology, South China Hospital, Medical School, Shenzhen University, Shenzhen, 518116, P. R. China.
Qi ZhuangDepartment of Urology, South China Hospital, Medical School, Shenzhen University, Shenzhen, 518116, P. R. China.
Rui LiangDepartment of Urology, South China Hospital, Medical School, Shenzhen University, Shenzhen, 518116, P. R. China.
Shaohua ZhangDepartment of Urology, South China Hospital, Medical School, Shenzhen University, Shenzhen, 518116, P. R. China.ORCID https://orcid.org/0000-0002-2396-6129
Song WuDepartment of Urology, Lanzhou University Second Hospital, Lanzhou, 730000, P. R. China.

Funding

National Natural Science Foundation of China 12326610National Natural Science Foundation of China 62425112National Natural Science Foundation of China 82102171National Natural Science Foundation of China 92359202Sanming Project of Medicine in Shenzhen SZSM202211009Shenzhen Engineering Research Center XMHT20220104016Shenzhen Medical Research Fund A2302048Shenzhen Science and Technology Innovation Commission RCJC20200714114557005Shenzhen Science and Technology Program JCYJ20230807141009020
6 · The paper itself

Abstract

Bladder cancer, a common malignancy of the urinary tract, presents complex therapeutic challenges, thereby necessitating the exploration of innovative treatment strategies. This study introduces a novel, self-propelled nanomedicine delivery system that forms nanoparticles within the bladder lumen by co-infusing dopamine hydrochloride, Mn

Indexed as

ImmunotherapyMembrane ProteinsNanoparticlesUrinary Bladder NeoplasmsAnimalsCell Line, TumorDrug Delivery SystemsFemaleHumansMiceMembrane Proteinsbladder cancercGAS‐STING pathwayimmunotherapyin situ polymerizationself‐propelled

Identifiers

PMID40135781
PMCPMC12224934

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.