Evidence map›Paper›PMID 40135756›Full record

ArticleThe British journal of psychiatry : the journal of mental science2026

Cognitive and clinical profiles in first-episode psychosis and their relationship with functional outcomes.

Megan Cowman, Jo Hodgekins, Siân Lowri Griffiths, Emma Frawley, Karen O'Connor, David Fowler, Max Birchwood, Gary Donohoe

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In one paragraph

Article in The British journal of psychiatry : the journal of mental science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Megan CowmanCentre for Neuroimaging, Cognition & Genomics (NICOG), School of Psychology, University of Galway, Galway, Ireland.
Jo HodgekinsDepartment of Clinical Psychology and Psychological Therapies, Norwich Medical School, University of East Anglia, Norwich, UK.
Siân Lowri GriffithsInstitute for Mental Health, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0003-0031-7174
Emma FrawleyCentre for Neuroimaging, Cognition & Genomics (NICOG), School of Psychology, University of Galway, Galway, Ireland.
Karen O'ConnorRISE Early Intervention in Psychosis Service, South Lee Mental Health Service, Cork, Ireland.
David FowlerPsychology Department, University of Sussex, Brighton, UK.
Max BirchwoodWarwick Medical School, University of Warwick, Coventry, UK.
Gary DonohoeCentre for Neuroimaging, Cognition & Genomics (NICOG), School of Psychology, University of Galway, Galway, Ireland.ORCID https://orcid.org/0000-0003-3037-7426

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile cognitive impairment is a core feature of psychosis, significant heterogeneity in cognitive and clinical outcomes is observed.

aimsThe aim of this study was to identify cognitive and clinical subgroups in first-episode psychosis (FEP) and determine if these profiles were linked to functional outcomes over time.

methodA total of 323 individuals with FEP were included. Two-step hierarchical and

resultsThree distinct cognitive clusters were identified: a cognitively intact group (

conclusionsBaseline cognitive impairments are predictive of both later social and occupational function and change over time. This suggests that cognitive profiles offer valuable information in terms of prognosis and treatment needs.

Indexed as

Cognitive DysfunctionPsychosocial FunctioningPsychotic DisordersAdolescentAdultCluster AnalysisFemaleHumansMaleSeverity of Illness IndexYoung Adultcluster analysiscognitionfunctional outcomePsychosissocial cognition

Identifiers

PMID40135756
PMCPMC12912872

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.