Evidence map›Paper›PMID 40135710›Full record

ArticlePerspectives in health information managemen2024

The Validation Of COVID-19 Information In The Pharmacoepidemiological Research Database of Spain's Public Health System Data by Vaccination Status.

Oliver Astasio, Belén Castillo-Cano, Beatriz Sánchez Delgado, Fabio Riefolo, Rosa Gini, Elisa Martín-Merino

Abstract readValidation Study
In one paragraph

Article in Perspectives in health information managemen, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Oliver Astasio
Belén Castillo-Cano
Beatriz Sánchez Delgado
Fabio Riefolo
Rosa Gini
Elisa Martín-Merino

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To validate COVID-19 information records in The Pharmacoepidemiological Research Database for Public Health System (BIFAP) of Spain. Methods: The recorded COVID-19 cases in primary care or positive test registries (gold-standard) were identified among vaccinated patients against COVID-19 infection and their matched unvaccinated controls, between December 2020 and October 2021. The sensitivity, specificity, positive (PPV) and negative (NPV) predictive values were estimated for primary care records. Results: Among 21,702 patients with positive tests and 20,866 with recorded COVID-19 diagnoses, the sensitivity, specificity, PPV and NPV were, respectively, 79.98 percent, 99.95 percent, 80.24 percent, and 99.94 percent among vaccinated, and 78.67 percent, 99.96 percent, 84.51 percent and 99.94 percent among controls. Conclusions: Primary care COVID-19 diagnosis recorded in BIFAP showed that sensitivity was similar and PPV was slightly lower among vaccinated than unvaccinated controls. Among the elderly, COVID-19 diagnosis was less recorded. These findings permit the design of informed algorithms for performing COVID-19-related studies.

Indexed as

COVID-19COVID-19 VaccinesDatabases, FactualPharmacoepidemiologyVaccinationAdolescentAdultAgedChildFemaleHumansMaleMiddle AgedPrimary Health CarePublic HealthSARS-CoV-2COVID-19 VaccinesCOVID-19electronic health recordsmeasurement errorspredictive values; misclassificationprimary carevaccination statusvalidation

Identifiers

PMID40135710
PMCPMC11102056

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.