Evidence map›Paper›PMID 40135565›Full record

ArticleJournal of the American Heart Association2025

Statin Use Among Women and Men Following Coronary Artery Bypass Surgery.

Sigrid Sandner, Alexandra Kaider, Julia Riebandt, Alissa Florian, Selma Rizvanovic, C Noel Bairey Merz, Jennifer S Lawton, Mary Charlson, Monika M Safford, Thomas Bergmair and 2 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Coronary artery surgery outcome differences by sex.Indian journal of thoracic and cardiovascular surgery · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sigrid SandnerDepartment of Cardiac Surgery Medical University Vienna Austria.ORCID 0000-0003-4669-9841
Alexandra KaiderInstitute of Clinical Biometrics, Center for Medical Data Science Medical University of Vienna Austria.
Julia RiebandtDepartment of Cardiac Surgery Medical University Vienna Austria.ORCID 0000-0002-8601-9989
Alissa FlorianDepartment of Cardiac Surgery Medical University Vienna Austria.
Selma RizvanovicDepartment of Cardiac Surgery Medical University Vienna Austria.
C Noel Bairey MerzBarbra Streisand Women's Heart Center, Smidt Heart Institute Cedars-Sinai Medical Center Los Angeles CA USA.ORCID 0000-0002-9933-5155
Jennifer S LawtonDivision of Cardiac Surgery, Department of Surgery Johns Hopkins University Baltimore MD USA.ORCID 0000-0002-0825-6591
Mary CharlsonDivision of Clinical Epidemiology and Evaluative Sciences Research, Department of Medicine Weill Cornell Medicine New York NY USA.ORCID 0000-0001-6487-1014
Monika M SaffordDepartment of Medicine Weill Cornell Medicine New York NY USA.ORCID 0000-0002-3060-0563
Thomas BergmairFederation of Social Insurances Vienna Austria.
Andreas ZuckermannDepartment of Cardiac Surgery Medical University Vienna Austria.ORCID 0000-0002-8054-8150
Mario GaudinoDepartment of Cardiothoracic Surgery, Weill Cornell Medicine New York Presbyterian Hospital New York NY USA.ORCID 0000-0003-4680-0815

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited data exist on sex differences in guideline-recommended statin therapy for secondary prevention after coronary artery bypass surgery (CABG). We examined sex differences in statin use after CABG and the association between sex-specific statin use and mortality. METHODS AND

resultsData from the Austrian national cardiac surgery registry and federal social insurance claims database for patients who underwent CABG between 2013 and 2021 were used. Multivariable logistic regression models were calculated to obtain women-to-men odds ratios for filling any statin and high-intensity statin prescriptions. Cox proportional hazards models were used to evaluate the association between statin use and mortality. A total of 15 448 patients (19% women) were included. During the 5 years after CABG, statin use decreased from 95.7% to 85.9% in men and 95.2% to 84.3% in women (P for trend <0.0001;

conclusionsWomen were as likely as men to fill a statin prescription after CABG and more likely to fill a high-intensity prescription. Statin use was associated with a similar mortality risk reduction among women and men.

Indexed as

Coronary Artery BypassCoronary Artery DiseaseHydroxymethylglutaryl-CoA Reductase InhibitorsSecondary PreventionAgedAustriaFemaleHumansMaleMiddle AgedRegistriesRetrospective StudiesRisk FactorsSex FactorsTreatment OutcomeHydroxymethylglutaryl-CoA Reductase Inhibitorscoronary artery bypass graftingsecondary preventionsex differencesstatins

Identifiers

PMID40135565
PMCPMC12132856

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.