Evidence map›Paper›PMID 40135561›Full record

ArticleJournal of the American Heart Association2025

Associations Between Measures of Structural Racism and Receipt of Acute Ischemic Stroke Interventions in the United States.

Amol M Mehta, Sai P Polineni, Praneet Polineni, Mandip S Dhamoon

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amol M MehtaDepartment of Neurology Icahn School of Medicine at Mount Sinai New York NY USA.ORCID 0000-0002-1343-7389
Sai P PolineniDepartment of Neurology Icahn School of Medicine at Mount Sinai New York NY USA.ORCID 0000-0002-2948-3275
Praneet PolineniFeinberg School of Medicine Northwestern University Chicago IL USA.ORCID 0000-0002-4981-4684
Mandip S DhamoonDepartment of Neurology Icahn School of Medicine at Mount Sinai New York NY USA.ORCID 0000-0003-2402-4632

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStructural racism and rural/urban differences in stroke care affect care delivery and outcomes. We explored the interplay among structural racism, urbanity, and intravenous thrombolysis (tissue plasminogen activator) and endovascular thrombectomy (ET). METHODS AND

resultsIn this retrospective study using complete, deidentified inpatient Medicare data (2016-2019), we identified incident acute ischemic stroke admissions, demographics, and hospital-level variables. Medicare beneficiaries aged ≥65 years with incident acute ischemic stroke admission in large metropolitan and nonurban settings were included. Validated structural racism metrics at the county level and a composite structural racism score that incorporated measures of segregation, housing, employment, education, and income were studied. Among 951 914 patients, rural hospitals demonstrated lower intensive care unit capacity (27.5% versus 88.6%), stroke certification (5.3% versus 38.4%), and rates of tissue plasminogen activator (1.6% versus 12.3%) and ET (<1% versus 3.8%). Large metropolitan areas demonstrated higher levels of income inequality (Gini index -0.15 versus 0.11 SD), and racial segregation (dissimilarity index 0.29 SD higher than the US mean). The composite structural racism score was associated with increased odds of tissue plasminogen activator receipt (odds ratio, 1.47 [95% CI, 1.33-1.63]) and ET (odds ratio, 4.15 [95% CI, 2.98-5.79]). Despite greater access to stroke care in urban areas, a persistent racial disparity remained, with Black patients less likely to receive tissue plasminogen activator (odds ratio, 0.70 [95% CI, 0.68-0.72]) and ET (odds ratio, 0.63 [95% CI, 0.60-0.66]) compared with White patients.

conclusionsWe found persistent disparities in stroke care access and outcomes, influenced by structural racism and rural-urban differences. Further research should explore interactions between structural racism, urbanity, and health care delivery to inform effective interventions.

Indexed as

Endovascular ProceduresHealthcare DisparitiesIschemic StrokeRacismThrombectomyThrombolytic TherapyAgedAged, 80 and overFemaleFibrinolytic AgentsHumansMaleMedicareRetrospective StudiesTissue Plasminogen ActivatorUnited StatesFibrinolytic AgentsTissue Plasminogen Activatoracute ischemic strokedisparitiesrural

Identifiers

PMID40135561
PMCPMC12132871

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.