Evidence map›Paper›PMID 40135556›Full record

ArticleJournal of the American Heart Association2025

Patterns and Outcomes of Endovascular Thrombectomy Among Patients Over Age 80 Years: The Florida Stroke Registry.

Vera Sharashidze, Hao Ying, Hannah E Gardener, Carolina M Gutierrez, Ayham Alkhachroum, Ruijie Yin, Lili Zhou, Gillian Gordon Perue, Angus Jameson, David Z Rose and 9 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Vera SharashidzeDepartment of Radiology NYU Langone Medical Center New York NY USA.ORCID 0000-0002-0862-1878
Hao YingDepartment of Neurology, Leonard M. Miller School of Medicine University of Miami FL USA.
Hannah E GardenerDepartment of Neurology, Leonard M. Miller School of Medicine University of Miami FL USA.ORCID 0000-0003-1416-632X
Carolina M GutierrezDepartment of Neurology, Leonard M. Miller School of Medicine University of Miami FL USA.ORCID 0000-0002-9879-3912
Ayham AlkhachroumDepartment of Neurology, Leonard M. Miller School of Medicine University of Miami FL USA.ORCID 0000-0003-0352-5913
Ruijie YinDepartment of Neurology, Leonard M. Miller School of Medicine University of Miami FL USA.ORCID 0000-0001-6375-2929
Lili ZhouDepartment of Neurology, Leonard M. Miller School of Medicine University of Miami FL USA.ORCID 0000-0002-9684-5993
Gillian Gordon PerueDepartment of Neurology, Leonard M. Miller School of Medicine University of Miami FL USA.ORCID 0000-0002-3991-3179
Angus JamesonUniversity of South Florida Morsani College of Medicine Tampa FL USA.ORCID 0000-0003-0944-8656
David Z RoseUniversity of South Florida Morsani College of Medicine Tampa FL USA.ORCID 0000-0002-9449-6494
Nicole B SurDepartment of Radiology NYU Langone Medical Center New York NY USA.ORCID 0000-0002-3541-3599
Victor J Del BruttoDepartment of Neurology, Leonard M. Miller School of Medicine University of Miami FL USA.ORCID 0000-0002-5115-6916
Ricardo HanelBaptist Neurological Institute Jacksonville FL USA.ORCID 0000-0001-7195-5806
Brijesh MehtaMemorial Regional Hosp Hollywood FL USA.ORCID 0000-0001-8332-2299
Dileep R YavagalDepartment of Neurology, Leonard M. Miller School of Medicine University of Miami FL USA.ORCID 0000-0003-4739-0133
Tatjana RundekDepartment of Neurology, Leonard M. Miller School of Medicine University of Miami FL USA.ORCID 0000-0002-7115-9815
Jose G RomanoDepartment of Neurology, Leonard M. Miller School of Medicine University of Miami FL USA.ORCID 0000-0003-3667-2792
Negar AsdaghiDepartment of Neurology, Leonard M. Miller School of Medicine University of Miami FL USA.ORCID 0000-0002-0285-825X
Florida Stroke Registry

Funding

The Data Management and BiostatisticsU54NS081763 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RUNDEK, TATJANA · 2013 to 2017
$4.2M
Miami Clinical and Translational Science Institute K12 ProgramK12TR004555 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALESSIA FORNONI, Tatjana Rundek · 2023 to 2026
$3.0M
Cross-disciplinary research opportunity for training in AD/ADRD science (CROSSROADS)T32AG081170 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI James E Galvin, Girardin Jean-Louis · 2024 to 2026
$1.4M
NCATS NIH HHS K12 TR004555NIA NIH HHS T32 AG081170NINDS NIH HHS U54 NS081763
6 · The paper itself

Abstract

backgroundOlder patients (≥80 years of age) were under-represented in randomized trials of endovascular thrombectomy (EVT). In the large Florida Stroke Registry (FSR), we aimed to evaluate the characteristics of the older patients receiving EVT in routine practice and to study the impact of age on EVT outcomes. METHODS AND

resultsData prospectively collected from Get With The Guidelines-Stroke hospitals in the FSR from January 2010 to December 2022 were analyzed for EVT outcomes. Among patients receiving EVT, characteristics associated with age ≥80 years and the impact of age on EVT outcomes of discharge directly to home or acute inpatient rehabilitation, and independent ambulation at discharge were studied using multivariable analysis with generalized estimating equations. Among 20 004 EVT FSR patients (mean age 71±15, 50% women), 29% were ≥80 years of age. In multivariable analysis, older patients with EVT had a similar rate of symptomatic intracerebral hemorrhage and in hospital mortality but were less likely to achieve independent ambulation at discharge (odds ratio [OR]: 0.44 [95% CI, 0.39-0.49]), be discharged directly home (OR: 0.46 [95% CI, 0.42-0.51]) or to a rehabilitation facility (OR: 0.68 [95% CI, 0.61-0.75]).

conclusionsIn routine practice, close to 30% of EVT treated stroke patients are over the age of 80 years. Our data shows that EVT is safe in this population; however, age remains an independent predictor of poor discharge outcomes post EVT.

Indexed as

Endovascular ProceduresStrokeThrombectomyAgedAged, 80 and overAge FactorsFemaleFloridaHospital MortalityHumansMalePatient DischargeProspective StudiesRegistriesStroke RehabilitationTreatment Outcomeambulationdischarge dispositionelderlyendovascular therapyischemic strokelarge vessel occlusion

Identifiers

PMID40135556
PMCPMC12132888

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.