Evidence map›Paper›PMID 40135110›Full record

ArticleClinicoEconomics and outcomes research : CEOR2025

The Burden of Obesity in Saudi Arabia: A Real-World Cost-of-Illness Study.

Mouaddh Abdulmalik Nagi, Ziyad Saeed Almalki, Montarat Thavorncharoensap, Sermsiri Sangroongruangsri, Saowalak Turongkaravee, Usa Chaikledkaew, Abdulhadi M Alqahtani, Lamis S AlSharif, Ibrahim A Alsubaihi, Abdulaziz I Alzarea and 1 more

Abstract read
In one paragraph

Article in ClinicoEconomics and outcomes research : CEOR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Observational
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  6. Burden of hypertension-related diseases in Eastern Mediterranean region.Journal of Taibah University Medical Sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mouaddh Abdulmalik NagiDoctor of Philosophy Program in Social, Economic, and Administrative Pharmacy, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.ORCID 0000-0003-4976-0978
Ziyad Saeed Almalki *Department of Clinical Pharmacy, Prince Sattam bin Abdulaziz University, Riyadh - Al-Kharj, Saudi Arabia.ORCID 0000-0003-1618-4142
Montarat Thavorncharoensap *Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Sermsiri SangroongruangsriDepartment of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.ORCID 0000-0002-5222-8694
Saowalak TurongkaraveeDepartment of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Usa ChaikledkaewDepartment of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Abdulhadi M AlqahtaniClinical Research Department, Research Center, King Fahad Medical City, Riyadh, Saudi Arabia.
Lamis S AlSharifClinical Research Department, Research Center, King Fahad Medical City, Riyadh, Saudi Arabia.
Ibrahim A AlsubaihiDepartment of Clinical Trials Support and Development, Saudi National Institute of Health, Riyadh, Saudi Arabia.
Abdulaziz I AlzareaDepartment of Clinical Pharmacy, Al-Jouf University College of Pharmacy, Sakaka, Saudi Arabia.ORCID 0000-0003-0604-6299
Mohammed M AlsultanDepartment of Pharmacy Practice, College of Clinical Pharmacy, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia.ORCID 0000-0002-9578-9790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The rising prevalence of obesity in the Kingdom of Saudi Arabia (KSA) poses a significant public health challenge. Estimates of the economic cost of obesity are crucial for prioritizing healthcare interventions, guiding policy choices, and justifying budget allocations aimed at reducing obesity prevalence. This study aimed to estimate the cost of obesity in the KSA in 2022. Methods: A prevalence-based cost-of-illness approach was used to determine the cost of obesity. This analysis encompasses 29 diseases, namely obesity and twenty-eight diseases attributable to obesity. Both direct and indirect costs were considered. The annual cost of treatment for each obesity-attributable disease was obtained from the hospital records of one tertiary hospital in the KSA. Data on direct non-medical costs were obtained from the patient survey. The human capital approach was used to estimate the indirect costs of morbidity and mortality. Results: The total economic burden of obesity (2022 values) was estimated at US$116.85 billion from a societal perspective and US$109.67 billion from a healthcare system perspective. From a societal perspective, the total direct medical cost accounted for the largest portion of the total cost (94%). In terms of direct medical costs, the cost of treating diseases attributable to obesity was substantially greater than the cost of treating obesity itself. According to the sensitivity analysis, the total cost ranged from 3.4% of the country's Gross domestic product (GDP) when the unit cost of treatment was reduced by 74% to 9.5% of the country's GDP when the prevalence of obesity and its comorbidities was reduced by 5%. Conclusion: Obesity imposes a substantial economic burden on the healthcare system and society in the KSA. Interventions aimed at promoting healthier lifestyles to reduce the prevalence and incidence of obesity and its comorbidities are highly warranted to alleviate the impact of obesity in the country.

Indexed as

body mass indexcost-of-illnesseconomic burdenobesitySaudi Arabia

Identifiers

PMID40135110
PMCPMC11934871

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.