Evidence map›Paper›PMID 40135045›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2025

Post COVID Condition and Long-Term COVID-19 Impact on Hepatic Decompensation and Survival in Cirrhosis: A Propensity Matched Observational Study.

Prerna Sharma, Madhumita Premkumar, Rashmi Ranjan Guru, Anchal Sandhu, Kamal Kajal, Arka De, Sahaj Rathi, Nipun Verma, Sunil Taneja, Virendra Singh and 1 more

Abstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Prerna SharmaDepartment of Hepatology Postgraduate Institute of Medical Education and Research Chandigarh India.
Madhumita PremkumarDepartment of Hepatology Postgraduate Institute of Medical Education and Research Chandigarh India.ORCID https://orcid.org/0000-0003-2961-4148
Rashmi Ranjan GuruDepartment of Hospital Administration Postgraduate Institute of Medical Education and Research Chandigarh India.
Anchal SandhuDepartment of Hepatology Postgraduate Institute of Medical Education and Research Chandigarh India.
Kamal KajalDepartment of Anesthesia and Critical Care Postgraduate Institute of Medical Education and Research Chandigarh India.
Arka DeDepartment of Hepatology Postgraduate Institute of Medical Education and Research Chandigarh India.ORCID https://orcid.org/0000-0002-8567-1676
Sahaj RathiDepartment of Hepatology Postgraduate Institute of Medical Education and Research Chandigarh India.
Nipun VermaDepartment of Hepatology Postgraduate Institute of Medical Education and Research Chandigarh India.
Sunil TanejaDepartment of Hepatology Postgraduate Institute of Medical Education and Research Chandigarh India.
Virendra SinghDepartment of Hepatology Postgraduate Institute of Medical Education and Research Chandigarh India.
Ajay Kumar DusejaDepartment of Hepatology Postgraduate Institute of Medical Education and Research Chandigarh India.ORCID https://orcid.org/0000-0003-3590-2664

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Patients with cirrhosis are susceptible to decompensation events, including ascites, variceal bleeding (VB), hepatic encephalopathy, or death after COVID-19 infection. Patients may experience post-COVID condition (PCC) with multisystem involvement that persists for at least 2 months. Methods: Hospitalized patients with cirrhosis and COVID-19 between January 2021 and January 2023 were assessed for decompensation events and mortality and compared to a propensity-matched cohort of cirrhosis and non-COVID-19 sepsis. Both groups were followed for outcomes over 1 year. Results: Of 252 patients with Cirrhosis+ COVID-19 (73% men, aged 48.9 ± 13.7 years, 31%-diabetes, 44%-hypertension, 35%-alcohol-associated, 34.5%-metabolic dysfunction-associated steatotic liver disease; MASLD), 72 (28.6%) died in hospital and 180 (71.4%) recovered, similar to Cirrhosis+ non-COVID-sepsis (58/214, 27.1%). Finally,60 (33.3%) met criteria for PCC, 19 (10.5%) had no post COVID-19 sequelae and 101 (56.1%) patients died ( Conclusion: COVID-19 is associated with long-term mortality in cirrhosis even after recovery from respiratory infection. Long COVID is seen in a third of COVID-19 survivors in patients with cirrhosis.

Indexed as

acute decompensation of cirrhosiscirrhosiscoronavirusCOVID‐19 liver failurelong COVID‐19portal hypertensionpost COVID conditionSARS‐CoV‐2viral pneumonia

Identifiers

PMID40135045
PMCPMC11932954

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.