Sevoflurane-Associated Acute Liver Injury in Renal Transplantation and Review of Literature.

Imran Gani, Nawal Moin, Jeffery Fallah, Ahmad Mirza

Abstract readCase Reports

In one paragraph

Article in Case reports in anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Imran GaniDepartment of Nephrology, Hypertension and Transplant Medicine, Augusta University Medical Center, Medical College of Georgia, 1120 15th St, Augusta 30912, Georgia, USA.ORCID https://orcid.org/0000-0002-4813-5022

Nawal MoinDepartment of Surgery, Augusta University Medical Center, Medical College of Georgia, 1120 15th St, Augusta 30912, Georgia, USA.

Jeffery FallahDepartment of Surgery, Augusta University Medical Center, Medical College of Georgia, 1120 15th St, Augusta 30912, Georgia, USA.

Ahmad MirzaDepartment of Surgery, Augusta University Medical Center, Medical College of Georgia, 1120 15th St, Augusta 30912, Georgia, USA.ORCID https://orcid.org/0000-0002-0568-9260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute liver injury can be precipitated by several factors perioperatively. One of the rare factors identified intraoperatively is the use of sevoflurane, an inhalational anesthetic agent which can cause significant acute hepatotoxicity. The report presents a case of acute liver injury followed by graft loss in a patient who underwent kidney transplantation. The patient developed several complications which resulted in graft loss. Close postoperative monitoring of patients following kidney transplantation is crucial. The case supports the current literature describing sevoflurane as a hepatotoxic agent. Medication side effects should be closely monitored both intraoperatively and postoperatively in those with renal dysfunction.

Indexed as

drug-induced acute liver injurygeneral anesthesiahalogenated hydrocarbonsimmunosuppressionkidney transplantationsevoflurane

Identifiers

PMID40134944

DOI10.1155/cria/1303993

PMCPMC11936524

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