ArticleFrontiers in neurology2025
'UltraGUD LP'-ultrasound guided diagnostic LP-a randomizedcontrolled trial. Traditional landmark based lumbar puncture is as effective as ultrasound guided lumbar puncture in outpatient neurology settings.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Ultrasound-Assisted Lumbar Puncture: A Narrative Review With Implications for Educators in the Clinical Neurosciences.Neurology. Education · 2026Review
- Predictors of post-lumbar puncture headache in an academic outpatient neurology setting: a retrospective exploratory study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Lumbar puncture (LP) is a fundamental procedure in neurology, yet its success is influenced by patient anatomy and provider expertise. Ultrasound guidance has been shown to improve outcomes in emergency and anesthesia settings, but its effectiveness in outpatient neurology remains unclear. Objective: This study (UltraGUD LP) aimed to compare the effectiveness of ultrasound-guided LP (US-LP) versus landmark-based LP (LM-LP) in an outpatient neurology setting, performed by a single experienced provider. Methods: A prospective randomized controlled trial was conducted from 2017 to 2022. Patients requiring LP were randomized to either LM-LP or US-LP. Success was defined as obtaining cerebrospinal fluid (CSF) within three attempts. Secondary outcomes included procedure time, incidence of traumatic taps, and post-LP headache rates. Results: Both techniques had comparable success rates, with LM-LP achieving 91% and US-LP 100% ( Conclusion: In a general outpatient neurology population, LM-LP is as effective as US-LP and requires less time. While US-LP may be beneficial for high-risk patients (e.g., obesity, prior back surgery), further studies are needed to confirm its superiority in these populations.
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