ArticleFrontiers in oncology2025
Histogram analysis of continuous-time random walk and restrictive spectrum imaging for identifying hepatocellular carcinoma and intrahepatic cholangiocarcinoma.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: To compare the ability and potential additional value of various diffusion models, including continuous-time random walk (CTRW), restrictive spectrum imaging (RSI), and diffusion-weighted imaging (DWI), as well as their associated histograms, in distinguishing the pathological subtypes of liver cancer. Methods: 40 patients with liver cancer were included in this study. Histogram metrics were derived from CTRW (D, α, β), RSI (f Results: Patients with hepatocellular carcinoma exhibited higher values in f Conclusion: CTRW, RSI, and their corresponding histogram parameters demonstrated the ability to distinguish between pathological subtypes of liver cancer. Moreover, whole-lesion histogram parameters provided more comprehensive statistical insights compared to mean values alone.
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