Evidence map›Paper›PMID 40134564›Full record

ReviewCytoJournal2025

The physiological and pathogenic roles of yes-associated protein/transcriptional co-activator with PDZ-binding motif in bone or skeletal motor system-related cells.

Yao Huang, Xueqian Ouyang, Jinghua Tan, Zhenyu Meng, Xiuwen Ma, Yiguo Yan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in CytoJournal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yao HuangDepartment of Spinal Surgery, Orthopaedic Research Center, The First Affiliated Hospital of the University of South China, Hengyang, China.ORCID https://orcid.org/0009-0001-4536-775X
Xueqian OuyangDepartment of Spinal Surgery, Orthopaedic Research Center, The First Affiliated Hospital of the University of South China, Hengyang, China.
Jinghua TanDepartment of Spinal Surgery, Orthopaedic Research Center, The First Affiliated Hospital of the University of South China, Hengyang, China.ORCID https://orcid.org/0000-0002-5165-3701
Zhenyu MengDepartment of Spinal Surgery, Orthopaedic Research Center, The First Affiliated Hospital of the University of South China, Hengyang, China.
Xiuwen MaDepartment of Spinal Surgery, Orthopaedic Research Center, The First Affiliated Hospital of the University of South China, Hengyang, China.ORCID https://orcid.org/0009-0001-4536-775X
Yiguo YanDepartment of Spinal Surgery, Orthopaedic Research Center, The First Affiliated Hospital of the University of South China, Hengyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are the primary downstream effectors of the Hippo signaling pathway. This pathway plays a crucial role in regulating organ size, maintaining tissue homeostasis, and controlling cellular processes such as fate determination and tissue development. This review provides an overview of the current understanding of how the transcriptional regulators YAP and TAZ contribute to the physiological and pathological processes in tissues and cells associated with the skeletal motor system. The underlying molecular mechanisms and mechanical transduction were reviewed.

Indexed as

BoneCartilageHeterotopic ossificationMesenchymal stem cellOsteoporosis

Identifiers

PMID40134564
PMCPMC11932947

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.