ArticleInternational journal of chronic obstructive pulmonary disease2025
Dynamic Risk Status of OSA and Its Association with COPD Incidence and Progression to Oxygen Therapy: Insights from a US National Cohort.
Article in International journal of chronic obstructive pulmonary disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Obstructive sleep apnea risk is associated with poor physical performance: a cross-sectional analysis of the U.S. health and retirement study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- The Natural History of Obstructive Sleep Apnea: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Novel murine partial tracheal occlusion model with altered respiratory dynamics.American journal of physiology. Lung cellular and molecular physiology · 2025Article
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Authors and funding
4 authors.
Funding
Abstract
Purpose: Obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) are prevalent respiratory disorders with significant health implications. This study investigates the relationship between OSA risk and the incidence and progression of COPD. Patients and Methods: We analyzed data from the Health and Retirement Study (HRS) cohort. Participants' OSA risk was assessed using the STOP-Bang questionnaire. Changes in OSA risk were evaluated by comparing baseline and follow-up assessments. COPD incidence and progression were determined through self-reported physician diagnoses and the use of oxygen therapy. After adjusting for covariates, hazard ratios (HR) and 95% confidence intervals (95% CI) were calculated using Cox proportional hazards models. Results: The analysis included 14398 participants for baseline OSA risk and 11177 for OSA risk changes. Participants with high baseline OSA risk had a significantly higher risk of developing COPD (adjusted HR: 1.255, 95% CI: 1.054-1.496) compared to those with low risk, although no significant relationship was found with progression to oxygen therapy. Participants whose OSA risk decreased showed a lower risk of developing COPD (Baseline low-risk group: adjusted HR: 0.603, 95% CI: 0.418-0.871; Baseline high-risk group: adjusted HR: 0.586, 95% CI: 0.396-0.869). This relationship was significant in women but not in men. Changes in OSA risk were not significantly related to COPD progression to oxygen therapy. Conclusion: OSA risk and its changes are associated with varying risks of COPD. Progression in OSA risk increases the risk of COPD, while improvement in OSA risk reduces it.
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