Evidence map›Paper›PMID 40134447›Full record

ArticleJournal of medicine and life2025

Collagen metabolism and incisional hernia recurrence: a comparative study between oncologic and non-oncologic patients.

Vlad Paic, Petru Adrian Radu, Anca Tigora, Mihai Zurzu, Mircea Bratucu, Costin Pasnicu, Alexandra Purcaru, Petru Stavar, Valeriu Surlin, Dan Cartu and 5 more

Abstract readComparative Study
In one paragraph

Article in Journal of medicine and life, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Vlad PaicTenth Department of Surgery, Carol Davila University of Medicine and Pharmacy Bucharest, Romania.
Petru Adrian RaduTenth Department of Surgery, Carol Davila University of Medicine and Pharmacy Bucharest, Romania.
Anca TigoraTenth Department of Surgery, Carol Davila University of Medicine and Pharmacy Bucharest, Romania.
Mihai ZurzuTenth Department of Surgery, Carol Davila University of Medicine and Pharmacy Bucharest, Romania.
Mircea BratucuTenth Department of Surgery, Carol Davila University of Medicine and Pharmacy Bucharest, Romania.
Costin PasnicuTenth Department of Surgery, Carol Davila University of Medicine and Pharmacy Bucharest, Romania.
Alexandra PurcaruTenth Department of Surgery, Carol Davila University of Medicine and Pharmacy Bucharest, Romania.
Petru StavarTenth Department of Surgery, Carol Davila University of Medicine and Pharmacy Bucharest, Romania.
Valeriu SurlinSixth Department of Surgery, University of Medicine and Pharmacy of Craiova, General Surgery Clinic I, Craiova Emergency Clinical Hospital, Craiova, Romania.
Dan CartuSixth Department of Surgery, University of Medicine and Pharmacy of Craiova, General Surgery Clinic I, Craiova Emergency Clinical Hospital, Craiova, Romania.
Daniela MarinescuSixth Department of Surgery, University of Medicine and Pharmacy of Craiova, General Surgery Clinic I, Craiova Emergency Clinical Hospital, Craiova, Romania.
Traean BurcosTenth Department of Surgery, Carol Davila University of Medicine and Pharmacy Bucharest, Romania.
Florian PopaTenth Department of Surgery, Carol Davila University of Medicine and Pharmacy Bucharest, Romania.
Victor StrambuTenth Department of Surgery, Carol Davila University of Medicine and Pharmacy Bucharest, Romania.
Dragos GarofilTenth Department of Surgery, Carol Davila University of Medicine and Pharmacy Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A significant challenge in incisional hernia repair is the recurrence risk, which may be influenced by the structural integrity of collagen within the tissue. This study investigated the role of collagen metabolism in hernia recurrence by comparing oncologic and non-oncologic patients, focusing on collagen I/III ratios and their impact on tissue strength and surgical outcomes. A comparative clinical study was conducted on 50 patients (30 oncologic, 20 non-oncologic) undergoing incisional hernia repair. Collagen composition was analyzed using stereomicroscopy, and statistical comparisons were performed using independent

Indexed as

CollagenIncisional HerniaNeoplasmsAdultAgedCollagen Type IFemaleHerniorrhaphyHumansMaleMiddle AgedRecurrenceCollagenCollagen Type Icollagen I/III ratiocollagen metabolismhernia recurrenceincisional herniaoncologic patientsstereomicroscopy

Identifiers

PMID40134447
PMCPMC11932504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.