ArticleJournal of Indian Society of Periodontology
Evaluation of antimicrobial activity of platelet-rich fibrin and titanium platelet-rich fibrin with and without incorporation of antibiotics on
Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Dose-dependent doxycycline local drug delivery using T-PRF: preliminary in vitro study.Scientific reports · 2026Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Infection control is of paramount importance after any periodontal therapy to achieve proper wound healing and regeneration of periodontal tissues. Clinicians continuously strive to provide procedures and/or materials that allow for enhanced and rapid wound healing. The regenerative potential of platelet concentrates like platelet-rich fibrin (PRF) has been explored for their anti-inflammatory action and liberation of growth factors; however, research is lacking on the antibacterial properties of platelet-rich gels. The present Materials and Methods: Thirty-three individuals who were willing to donate blood (12 ml) were included in the study. Amoxicillin (AMOX) + metronidazole (METRO) combination or clindamycin (CLINDA) was incorporated into the blood drawn, and this blood was subjected to centrifugation so as to obtain T-PRF and PRF with antibiotics. The antibacterial activity of all the groups was tested on both bacteria that were cultured in their respective media for up to a 4-day period. The data were subjected to independent Results: All individual parameters were compared for antimicrobial activity on both bacteria on all 4 days. A highly statistical difference ( Conclusion: T-PRF/PRF with and without antibiotics exhibited antimicrobial activity on
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